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Bioorganic Chemistry|May 21, 2023
Targeting the Grb2 cSH3 domain: Design, synthesis and biological evaluation of the first series of modulatorsMarianna Bufano, Michela Puxeddu, Marianna Nalli, et al.Cancers|March 10, 2022
Anticancer Activity of (S)-5-Chloro-3-((3,5-dimethylphenyl)sulfonyl)-N-(1-oxo-1-((pyridin-4-ylmethyl)amino)propan-2-yl)-1H-indole-2-carboxamide (RS4690), a New Dishevelled 1 InhibitorAntonio Coluccia, Marianna Bufano, Giuseppe La Regina, et al.Chemical Science|May 22, 2018
Folding mechanisms steer the amyloid fibril formation propensity of highly homologous proteinsGaetano Malgieri, Gianluca D'Abrosca, Luciano Pirone, et al.Journal of Molecular Biology|January 22, 2025
The Critical Role of the Variable Domain in Driving Proteotoxicity and Aggregation in Full-length Light ChainsSarita Puri, Angela Gadda, Ivan Polsinelli, et al.Journal of Medicinal Chemistry|June 12, 2026
(S,S)-5-Chloro-3-((3,5-dimethylphenyl)sulfonyl)-N-(1-oxo-1-((1-(pyridin-4-yl)ethyl)amino)propan-2-yl)-1H-indole-2-carboxamide, a New Dishevelled 1 and P-Glycoprotein Dual Inhibitor as a Anticancer AgentMichela Puxeddu, Zeyu Cui, Claudia Colla, et al.Pageof 8