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Briefings in Bioinformatics|August 23, 2024
Harnessing large language models' zero-shot and few-shot learning capabilities for regulatory researchHamed Meshkin, Joel Zirkle, Ghazal Arabidarrehdor, et al.
BMC Bioinformatics|November 2, 2023
Deep learning-enabled natural language processing to identify directional pharmacokinetic drug-drug interactionsJoel Zirkle, Xiaomei Han, Rebecca Racz, et al.
Scientific Reports|May 27, 2024
Mechanism-based organization of neural networks to emulate systems biology and pharmacology modelsJohn Mann, Hamed Meshkin, Joel Zirkle, et al.
Clinical and Translational Science|April 15, 2024
Physiologically based modeling reveals different risk of respiratory depression after fentanyl overdose between adults and childrenShilpa Chakravartula, Bradlee Thrasher, John Mann, et al.
Clinical Pharmacology and Therapeutics|January 29, 2025
Toward Developing Alternative Opioid Antagonists for Treating Community Overdose: A Model-Based Evaluation of Important Pharmacological AttributesAnik Chaturbedi, John Mann, Shilpa Chakravartula, et al.
Clinical Pharmacology and Therapeutics|June 13, 2022
Calibration and Validation of a Mechanistic COVID-19 Model for Translational Quantitative Systems Pharmacology - A Proof-of-Concept Model Development for RemdesivirMohammadreza Samieegohar, James L Weaver, Kristina E Howard, et al.
Clinical Pharmacology and Therapeutics|January 11, 2026
Modeling Supports Combinatorial Effects Between Pharmacological and Non-Pharmacological Interventions to Prevent Opioid-Induced Cardiac ArrestBradlee Thrasher, John Mann, Anik Chaturbedi, et al.
Clinical Pharmacology and Therapeutics|February 2, 2026
Clinical Study to Evaluate Drug Interactions of Cannabidiol with Citalopram and Morphine in Healthy AdultsPablo Salcedo, Donna A Volpe, Anik Chaturbedi, et al.
Clinical Pharmacology and Therapeutics|June 29, 2022
Development of a Translational Model to Assess the Impact of Opioid Overdose and Naloxone Dosing on Respiratory Depression and Cardiac ArrestJohn Mann, Mohammadreza Samieegohar, Anik Chaturbedi, et al.
JAMA Network Open|January 23, 2024
Intranasal Naloxone Repeat Dosing Strategies and Fentanyl Overdose: A Simulation-Based Randomized Clinical TrialDavid G Strauss, Zhihua Li, Anik Chaturbedi, et al.
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