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Bioorganic & Medicinal Chemistry Letters|March 5, 2017
Synthesis and evaluation of 5-(arylthio)-9H-pyrimido[4,5-b]indole-2,4-diamines as receptor tyrosine kinase and thymidylate synthase inhibitors and as antitumor agentsNilesh Zaware, Roy Kisliuk, Anja Bastian, et al.Therapeutic Advances in Medical Oncology|March 2, 2016
Targeting dormant micrometastases: rationale, evidence to date and clinical implicationsRobert E Hurst, Anja Bastian, Lora Bailey-Downs, et al.BMC Cancer|July 17, 2015
A new anti-glioma therapy, AG119: pre-clinical assessment in a mouse GL261 glioma modelRheal A Towner, Michael Ihnat, Debra Saunders, et al.Bioorganic & Medicinal Chemistry|November 30, 2016
Discovery and preclinical evaluation of 7-benzyl-N-(substituted)-pyrrolo[3,2-d]pyrimidin-4-amines as single agents with microtubule targeting effects along with triple-acting angiokinase inhibition as antitumor agentsRoheeth Kumar Pavana, Shruti Choudhary, Anja Bastian, et al.Bioorganic & Medicinal Chemistry|April 18, 2015
The design, synthesis and biological evaluation of conformationally restricted 4-substituted-2,6-dimethylfuro[2,3-d]pyrimidines as multi-targeted receptor tyrosine kinase and microtubule inhibitors as potential antitumor agentsXin Zhang, Sudhir Raghavan, Michael Ihnat, et al.Bioorganic & Medicinal Chemistry|February 26, 2013
Synthesis and biological activity of 5-chloro-N⁴-substituted phenyl-9H-pyrimido[4,5-b]indole-2,4-diamines as vascular endothelial growth factor receptor-2 inhibitors and antiangiogenic agentsAleem Gangjee, Nilesh Zaware, Sudhir Raghavan, et al.Journal of Immunology Research|May 11, 2019
Interleukin 6 Function in the Skin and Isolated Keratinocytes Is Modulated by HyperglycemiaEric G Lee, Lerin R Luckett-Chastain, Kaitlin N Calhoun, et al.Cancer Letters|December 13, 2016
AG311, a small molecule inhibitor of complex I and hypoxia-induced HIF-1α stabilizationAnja Bastian, Satoshi Matsuzaki, Kenneth M Humphries, et al.ACS Medicinal Chemistry Letters|June 6, 2014
Discovery of antitubulin agents with antiangiogenic activity as single entities with multitarget chemotherapy potentialAleem Gangjee, Roheeth Kumar Pavana, Michael A Ihnat, et al.Plos One|June 1, 2014
Development and characterization of a preclinical model of breast cancer lung micrometastatic to macrometastatic progressionLora C Bailey-Downs, Jessica E Thorpe, Bryan C Disch, et al.Pageof 2