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The Journal of Biological Chemistry|December 14, 2004
Gamma-secretase complex assembly within the early secretory pathwayAnja Capell, Dirk Beher, Stefan Prokop, et al.
The Journal of Cell Biology|July 31, 2002
Presenilin-1 affects trafficking and processing of betaAPP and is targeted in a complex with nicastrin to the plasma membraneChristoph Kaether, Sven Lammich, Dieter Edbauer, et al.
The Journal of Biological Chemistry|November 7, 2007
Missense mutations in the progranulin gene linked to frontotemporal lobar degeneration with ubiquitin-immunoreactive inclusions reduce progranulin production and secretionSunita S Shankaran, Anja Capell, Alexander T Hruscha, et al.
Acta Neuropathologica Communications|January 28, 2023
Lack of a protective effect of the Tmem106b "protective SNP" in the Grn knockout mouse model for frontotemporal lobar degenerationAnne-Sophie Cabron, Uwe Borgmeyer, Julia Richter, et al.
Neurobiology of Aging|January 27, 2016
Reduced secretion and altered proteolytic processing caused by missense mutations in progranulinGernot Kleinberger, Anja Capell, Nathalie Brouwers, et al.
Molecular Neurodegeneration|September 6, 2018
Early lysosomal maturation deficits in microglia triggers enhanced lysosomal activity in other brain cells of progranulin knockout miceJulia K Götzl, Alessio-Vittorio Colombo, Katrin Fellerer, et al.
The Journal of Biological Chemistry|April 19, 2012
Membrane orientation and subcellular localization of transmembrane protein 106B (TMEM106B), a major risk factor for frontotemporal lobar degenerationChristina M Lang, Katrin Fellerer, Benjamin M Schwenk, et al.
Journal of Neurochemistry|June 18, 2002
A non-amyloidogenic function of BACE-2 in the secretory pathwayRegina Fluhrer, Anja Capell, Gil Westmeyer, et al.
EMBO Molecular Medicine|July 13, 2016
TREM2 deficiency reduces the efficacy of immunotherapeutic amyloid clearanceXianyuan Xiang, Georg Werner, Bernd Bohrmann, et al.
The Journal of Biological Chemistry|September 12, 2002
Presenilin-dependent intramembrane proteolysis of CD44 leads to the liberation of its intracellular domain and the secretion of an Abeta-like peptideSven Lammich, Masayasu Okochi, Masatoshi Takeda, et al.
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