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Bioorganic & Medicinal Chemistry Letters|September 4, 2007
Dual serotonin transporter inhibitor/histamine H3 antagonists: development of rigidified H3 pharmacophoresJohn M Keith, Ann J Barbier, Sandy J Wilson, et al.Bioorganic & Medicinal Chemistry Letters|July 10, 2007
Benzylamine histamine H(3) antagonists and serotonin reuptake inhibitorsMichael A Letavic, Emily M Stocking, Ann J Barbier, et al.Journal of Medicinal Chemistry|March 18, 2005
4-phenoxypiperidines: potent, conformationally restricted, non-imidazole histamine H3 antagonistsCurt A Dvorak, Richard Apodaca, Ann J Barbier, et al.Clinical Therapeutics|December 3, 2014
Pharmacodynamics, pharmacokinetics, safety, and tolerability of encenicline, a selective α7 nicotinic receptor partial agonist, in single ascending-dose and bioavailability studiesAnn J Barbier, Martijn Hilhorst, André Van Vliet, et al.Bioorganic & Medicinal Chemistry Letters|February 20, 2007
Novel naphthyridines are histamine H3 antagonists and serotonin reuptake transporter inhibitorsMichael A Letavic, John M Keith, Kiev S Ly, et al.Bioorganic & Medicinal Chemistry|February 6, 2008
Lead identification of acetylcholinesterase inhibitors-histamine H3 receptor antagonists from molecular modelingScott D Bembenek, John M Keith, Michael A Letavic, et al.Bioorganic & Medicinal Chemistry Letters|June 23, 2007
Pyrrolidino-tetrahydroisoquinolines bearing pendant heterocycles as potent dual H3 antagonist and serotonin transporter inhibitorsJohn M Keith, Leslie A Gomez, Ann J Barbier, et al.Genetics in Medicine : Official Journal of the American College of Medical Genetics|April 4, 2015
A phase I/II study of intrathecal idursulfase-IT in children with severe mucopolysaccharidosis IIJoseph Muenzer, Christian J Hendriksz, Zheng Fan, et al.Bioorganic & Medicinal Chemistry Letters|April 7, 2007
Synthesis and biological evaluation of diamine-based histamine H3 antagonists with serotonin reuptake inhibitor activityEmily M Stocking, Jennifer M Miller, Ann J Barbier, et al.Clinical Pharmacology in Drug Development|August 10, 2018
Phase 1 Single- and Multiple-Ascending-Dose Randomized Studies of the Safety, Pharmacokinetics, and Pharmacodynamics of AG-348, a First-in-Class Allosteric Activator of Pyruvate Kinase R, in Healthy VolunteersHua Yang, Elizabeth Merica, Yue Chen, et al.Pageof 4