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The Journal of Biological Chemistry|March 23, 2021
Crystal structures of NUDT15 variants enabled by a potent inhibitor reveal the structural basis for thiopurine sensitivityDaniel Rehling, Si Min Zhang, Ann-Sofie Jemth, et al.
Nature|April 4, 2014
Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategyKilian V M Huber, Eidarus Salah, Branka Radic, et al.
Viruses|December 16, 2020
Novel Broad-Spectrum Antiviral Inhibitors Targeting Host Factors Essential for Replication of Pathogenic RNA VirusesMarianna Tampere, Aleksandra Pettke, Cristiano Salata, et al.
Journal of Medicinal Chemistry|February 2, 2017
Identification of Triazolothiadiazoles as Potent Inhibitors of the dCTP Pyrophosphatase 1Sabin Llona-Minguez, Andreas Höglund, Elisee Wiita, et al.
Cell Chemical Biology|June 30, 2021
NUDT15-mediated hydrolysis limits the efficacy of anti-HCMV drug ganciclovirSi Min Zhang, Daniel Rehling, Ann-Sofie Jemth, et al.
Nature Communications|November 17, 2017
A comprehensive structural, biochemical and biological profiling of the human NUDIX hydrolase familyJordi Carreras-Puigvert, Marinka Zitnik, Ann-Sofie Jemth, et al.
Nature Communications|January 19, 2018
Targeted NUDT5 inhibitors block hormone signaling in breast cancer cellsBrent D G Page, Nicholas C K Valerie, Roni H G Wright, et al.
Nature Communications|November 3, 2019
Author Correction: Targeted NUDT5 inhibitors block hormone signaling in breast cancer cellsBrent D G Page, Nicholas C K Valerie, Roni H G Wright, et al.
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