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The Journal of Pharmacology and Experimental Therapeutics|June 12, 2024
AAV9-Mediated Intrastriatal Delivery of GNAO1 Reduces Hyperlocomotion in Gnao1 Heterozygous R209H Mutant MiceAlex J Roy, Jeffrey R Leipprandt, Joseph R Patterson, et al.
Toxicological Sciences : an Official Journal of the Society of Toxicology|August 22, 2023
Developmental exposure to the Parkinson's disease-associated organochlorine pesticide dieldrin alters dopamine neurotransmission in α-synuclein pre-formed fibril (PFF)-injected miceSierra L Boyd, Nathan C Kuhn, Joseph R Patterson, et al.
The European Journal of Neuroscience|February 15, 2024
Deficits in basal and evoked striatal dopamine release following alpha-synuclein preformed fibril injection: An in vivo microdialysis studyAshley Centner, Isabella Del Priore, Nicole Chambers, et al.
Neurobiology of Disease|July 6, 2019
Time course and magnitude of alpha-synuclein inclusion formation and nigrostriatal degeneration in the rat model of synucleinopathy triggered by intrastriatal α-synuclein preformed fibrilsJoseph R Patterson, Megan F Duffy, Christopher J Kemp, et al.
NPJ Parkinson'S Disease|May 24, 2022
Beta2-adrenoreceptor agonist clenbuterol produces transient decreases in alpha-synuclein mRNA but no long-term reduction in proteinJoseph R Patterson, Warren D Hirst, Jacob W Howe, et al.
Frontiers in Neuroscience|April 16, 2025
Intrastriatal injection of alpha-synuclein preformed fibrils to rats results in L-DOPA reversible sensorimotor impairments and alterations in non-motor functionSheila M Fleming, Sophia Scott, Edward J Hamad, et al.
NPJ Parkinson'S Disease|January 3, 2024
Transcriptomic profiling of early synucleinopathy in rats induced with preformed fibrilsJoseph R Patterson, Joseph Kochmanski, Anna C Stoll, et al.
Biorxiv : the Preprint Server for Biology|September 15, 2025
Tau, amyloid-β and α-synuclein co-pathologies synergistically enhance neuroinflammation and neuropathologyJhodi M Webster, Ya-Ting Yang, Aidan T Miller, et al.
Neurobiology of Disease|February 26, 2026
Tau, amyloid-β and α-synuclein co-pathologies synergistically enhance neuroinflammation and hippocampal neuron lossJhodi M Webster, Ya-Ting Yang, Aidan T Miller, et al.
Neurobiology of Disease|June 9, 2026
Human TDP-43 expression worsens FTD-related phenotypes in progranulin-insufficient miceAnna K Cook, Benjamin Lin, Yumo Song, et al.
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