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Molecular Cancer Therapeutics|November 1, 2023
Improving Intracellular Delivery of an Antibody-Drug Conjugate Targeting Carcinoembryonic Antigen Increases Efficacy at Clinically Relevant Doses In VivoIan Nessler, Baron Rubahamya, Anna Kopp, et al.Journal of Theoretical Biology|September 15, 2012
A mechanistic compartmental model for total antibody uptake in tumorsGreg M Thurber, K Dane WittrupCancer Research|May 3, 2008
Quantitative spatiotemporal analysis of antibody fragment diffusion and endocytic consumption in tumor spheroidsGreg M Thurber, K Dane WittrupPharmaceutics|February 9, 2020
Practical Guide for Quantification of In Vivo Degradation Rates for Therapeutic Proteins with Single-Cell Resolution Using Fluorescence Ratio ImagingIan Nessler, Cornelius Cilliers, Greg M ThurberTrends in Biochemical Sciences|December 20, 2018
Hitting Undruggable Targets: Viewing Stabilized Peptide Development through the Lens of Quantitative Systems PharmacologyLydia Atangcho, Tejas Navaratna, Greg M ThurberTrends in Pharmacological Sciences|August 30, 2021
Key metrics to expanding the pipeline of successful antibody-drug conjugatesIan Nessler, Bruna Menezes, Greg M ThurberBioconjugate Chemistry|June 22, 2016
A Helix-Stabilizing Linker Improves Subcutaneous Bioavailability of a Helical Peptide Independent of Linker LipophilicityLiang Zhang, Tejas Navaratna, Greg M ThurberScience Advances|May 31, 2024
Clinical translation of antibody drug conjugate dosing in solid tumors from preclinical mouse dataBaron Rubahamya, Shujun Dong, Greg M ThurberPlos One|December 4, 2009
Multicolor fluorescent intravital live microscopy (FILM) for surgical tumor resection in a mouse xenograft modelGreg M Thurber, Jose L Figueiredo, Ralph WeisslederMolecular Cancer Therapeutics|December 30, 2025
In vivo Auto-tuning of Antibody-Drug Conjugate Delivery to Maximize Efficacy using High-Avidity, Low-Affinity AntibodiesAnna Kopp, Shujun Dong, Hyeyoung Kwon, et al.Pageof 7