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Frontiers in Pharmacology|June 11, 2019
Computational Identification of Novel Kir6 Channel InhibitorsXingyu Chen, Arthur Garon, Marcus Wieder, et al.
British Journal of Pharmacology|January 15, 2025
Ethosuximide: Subunit- and Gβγ-dependent blocker and reporter of allosteric changes in GIRK channelsBoris Shalomov, Theres Friesacher, Daniel Yakubovich, et al.
American Journal of Physiology. Heart and Circulatory Physiology|August 12, 2025
The sodium/glucose cotransporter 2 inhibitor empagliflozin is a pharmacological chaperone of cardiac Na<sub>v</sub>1.5 channelsJakob Sauer, Jessica Marksteiner, Martin Hohenegger, et al.
Frontiers in Pharmacology|May 19, 2022
The Bradycardic Agent Ivabradine Acts as an Atypical Inhibitor of Voltage-Gated Sodium ChannelsBenjamin Hackl, Peter Lukacs, Janine Ebner, et al.
British Journal of Pharmacology|October 17, 2024
Development of new K<sub>ir</sub>2.1 channel openers from propafenone analoguesEncan Li, Najla Boujeddaine, Marien J C Houtman, et al.
Journal of Biomedical Science|July 17, 2017
PA-6 inhibits inward rectifier currents carried by V93I and D172N gain-of-function K<sub>IR</sub>2.1 channels, but increases channel protein expressionYuan Ji, Marlieke G Veldhuis, Jantien Zandvoort, et al.
Pharmacological Research|February 26, 2018
Dehydroevodiamine and hortiamine, alkaloids from the traditional Chinese herbal drug Evodia rutaecarpa, are I<sub>Kr</sub> blockers with proarrhythmic effects in vitro and in vivoIgor Baburin, Rosanne Varkevisser, Anja Schramm, et al.
Cardiovascular Research|April 30, 2013
Efficient and specific cardiac IK₁ inhibition by a new pentamidine analogueHiroki Takanari, Lukas Nalos, Anna Stary-Weinzinger, et al.
Molecular Pharmacology|April 4, 2020
LUF7244 plus Dofetilide Rescues Aberrant K<sub>v</sub>11.1 Trafficking and Produces Functional I<sub>Kv11.1</sub>Muge Qile, Yuan Ji, Tyona D Golden, et al.
Nature Communications|November 25, 2025
Live-cell quantitative monitoring reveals distinct, high-affinity Gβγ regulations of GIRK2 and GIRK1/2 channelsReem Handklo-Jamal, Tal Keren Raifman, Boris Shalomov, et al.
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