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The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|June 14, 2013
AZ-4217: a high potency BACE inhibitor displaying acute central efficacy in different in vivo models and reduced amyloid deposition in Tg2576 miceSusanna Eketjäll, Juliette Janson, Fredrik Jeppsson, et al.Frontiers in Neuroscience|August 10, 2018
Clusterin Is Required for β-Amyloid Toxicity in Human iPSC-Derived NeuronsJacqueline P Robbins, Leo Perfect, Elena M Ribe, et al.Molecular Metabolism|March 16, 2021
Suppression of insulin-induced gene 1 (INSIG1) function promotes hepatic lipid remodelling and restrains NASH progressionVian Azzu, Michele Vacca, Ioannis Kamzolas, et al.Diabetes|December 29, 2022
Elevated Adipocyte Membrane Phospholipid Saturation Does Not Compromise Insulin SignalingHenrik Palmgren, Kasparas Petkevicius, Stefano Bartesaghi, et al.BMC Biology|January 17, 2019
In vivo genome and base editing of a human PCSK9 knock-in hypercholesterolemic mouse modelAlba Carreras, Luna Simona Pane, Roberto Nitsch, et al.Toxicological Sciences : an Official Journal of the Society of Toxicology|May 1, 2007
Tesaglitazar, a PPARalpha/gamma agonist, induces interstitial mesenchymal cell DNA synthesis and fibrosarcomas in subcutaneous tissues in ratsHeike Hellmold, Hui Zhang, Ulf Andersson, et al.Liver International : Official Journal of the International Association for the Study of the Liver|October 22, 2020
PCSK9 rs11591147 R46L loss-of-function variant protects against liver damage in individuals with NAFLDStefania Grimaudo, Stefano Bartesaghi, Raffaela Rametta, et al.Nature Communications|January 22, 2021
Universal toxin-based selection for precise genome engineering in human cellsSongyuan Li, Nina Akrap, Silvia Cerboni, et al.Molecular Metabolism|February 18, 2019
Pnpla3 silencing with antisense oligonucleotides ameliorates nonalcoholic steatohepatitis and fibrosis in Pnpla3 I148M knock-in miceDaniel Lindén, Andrea Ahnmark, Piero Pingitore, et al.Nature|September 14, 2018
In vivo CRISPR editing with no detectable genome-wide off-target mutationsPinar Akcakaya, Maggie L Bobbin, Jimmy A Guo, et al.Pageof 12