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Bioconjugate Chemistry
|
May 3, 2017
Synthesis and Evaluation of Parenchymal Retention and Efficacy of a Metabolically Stable O-Phosphocholine-N-docosahexaenoyl-l-serine siRNA Conjugate in Mouse Brain
Mehran Nikan, Maire F Osborn, Andrew H Coles, et al.
Molecular Therapy : the Journal of the American Society of Gene Therapy
|
June 26, 2018
Optimized Cholesterol-siRNA Chemistry Improves Productive Loading onto Extracellular Vesicles
Reka Agnes Haraszti, Rachael Miller, Marie-Cecile Didiot, et al.
Journal of Magnetic Resonance (San Diego, Calif. : 1997)
|
January 10, 2025
<sup>1</sup>H-<sup>19</sup>F cross-polarization magic angle spinning dynamic nuclear polarization NMR investigation of advanced pharmaceutical formulations
Mária Šoltésová, Arthur C Pinon, Fabien Aussenac, et al.
Molecular Therapy. Nucleic Acids
|
July 18, 2022
Chemical optimization of siRNA for safe and efficient silencing of placental sFLT1
Sarah M Davis, Vignesh N Hariharan, Agnes Lo, et al.
Nucleic Acids Research
|
December 12, 2018
Hydrophobicity drives the systemic distribution of lipid-conjugated siRNAs via lipid transport pathways
Maire F Osborn, Andrew H Coles, Annabelle Biscans, et al.
Molecular Therapy : the Journal of the American Society of Gene Therapy
|
April 28, 2022
RNAi-based modulation of IFN-γ signaling in skin
Qi Tang, Jacquelyn Sousa, Dimas Echeverria, et al.
Molecular Therapy : the Journal of the American Society of Gene Therapy
|
August 26, 2018
Transvascular Delivery of Hydrophobically Modified siRNAs: Gene Silencing in the Rat Brain upon Disruption of the Blood-Brain Barrier
Bruno M D C Godinho, Nils Henninger, James Bouley, et al.
Molecular Therapy. Nucleic Acids
|
July 7, 2022
PK-modifying anchors significantly alter clearance kinetics, tissue distribution, and efficacy of therapeutics siRNAs
Bruno M D C Godinho, Emily G Knox, Samuel Hildebrand, et al.
Science Advances
|
August 21, 2021
Gene therapy with AR isoform 2 rescues spinal and bulbar muscular atrophy phenotype by modulating AR transcriptional activity
Wooi F Lim, Mitra Forouhan, Thomas C Roberts, et al.
Nature Biotechnology
|
August 1, 2024
Enhancing siRNA efficacy in vivo with extended nucleic acid backbones
Ken Yamada, Vignesh N Hariharan, Jillian Caiazzi, et al.
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Search research articles
Search
Showing results (21-30 of 32) with videos related to
Sort By:
Page
of 4
Bioconjugate Chemistry
|
May 3, 2017
Synthesis and Evaluation of Parenchymal Retention and Efficacy of a Metabolically Stable O-Phosphocholine-N-docosahexaenoyl-l-serine siRNA Conjugate in Mouse Brain
Mehran Nikan, Maire F Osborn, Andrew H Coles, et al.
Molecular Therapy : the Journal of the American Society of Gene Therapy
|
June 26, 2018
Optimized Cholesterol-siRNA Chemistry Improves Productive Loading onto Extracellular Vesicles
Reka Agnes Haraszti, Rachael Miller, Marie-Cecile Didiot, et al.
Journal of Magnetic Resonance (San Diego, Calif. : 1997)
|
January 10, 2025
<sup>1</sup>H-<sup>19</sup>F cross-polarization magic angle spinning dynamic nuclear polarization NMR investigation of advanced pharmaceutical formulations
Mária Šoltésová, Arthur C Pinon, Fabien Aussenac, et al.
Molecular Therapy. Nucleic Acids
|
July 18, 2022
Chemical optimization of siRNA for safe and efficient silencing of placental sFLT1
Sarah M Davis, Vignesh N Hariharan, Agnes Lo, et al.
Nucleic Acids Research
|
December 12, 2018
Hydrophobicity drives the systemic distribution of lipid-conjugated siRNAs via lipid transport pathways
Maire F Osborn, Andrew H Coles, Annabelle Biscans, et al.
Molecular Therapy : the Journal of the American Society of Gene Therapy
|
April 28, 2022
RNAi-based modulation of IFN-γ signaling in skin
Qi Tang, Jacquelyn Sousa, Dimas Echeverria, et al.
Molecular Therapy : the Journal of the American Society of Gene Therapy
|
August 26, 2018
Transvascular Delivery of Hydrophobically Modified siRNAs: Gene Silencing in the Rat Brain upon Disruption of the Blood-Brain Barrier
Bruno M D C Godinho, Nils Henninger, James Bouley, et al.
Molecular Therapy. Nucleic Acids
|
July 7, 2022
PK-modifying anchors significantly alter clearance kinetics, tissue distribution, and efficacy of therapeutics siRNAs
Bruno M D C Godinho, Emily G Knox, Samuel Hildebrand, et al.
Science Advances
|
August 21, 2021
Gene therapy with AR isoform 2 rescues spinal and bulbar muscular atrophy phenotype by modulating AR transcriptional activity
Wooi F Lim, Mitra Forouhan, Thomas C Roberts, et al.
Nature Biotechnology
|
August 1, 2024
Enhancing siRNA efficacy in vivo with extended nucleic acid backbones
Ken Yamada, Vignesh N Hariharan, Jillian Caiazzi, et al.
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