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Molecular Biology of the Cell|January 3, 2024
From pixels to phenotypes: Integrating image-based profiling with cell health data as BioMorph features improves interpretabilitySrijit Seal, Jordi Carreras-Puigvert, Shantanu Singh, et al.Science (New York, N.Y.)|November 5, 2011
mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H(+)-ATPaseRoberto Zoncu, Liron Bar-Peled, Alejo Efeyan, et al.Nature|August 4, 2016
Mechanism of arginine sensing by CASTOR1 upstream of mTORC1Robert A Saxton, Lynne Chantranupong, Kevin E Knockenhauer, et al.Science (New York, N.Y.)|September 5, 2015
Identification of an oncogenic RAB proteinDouglas B Wheeler, Roberto Zoncu, David E Root, et al.Nature Methods|August 25, 2006
Genome-scale loss-of-function screening with a lentiviral RNAi libraryDavid E Root, Nir Hacohen, William C Hahn, et al.Arxiv|July 1, 2024
Learning Molecular Representation in a CellGang Liu, Srijit Seal, John Arevalo, et al.Nature Communications|August 2, 2024
Evaluating batch correction methods for image-based cell profilingJohn Arevalo, Ellen Su, Jessica D Ewald, et al.Cell|April 13, 2010
Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acidsYasemin Sancak, Liron Bar-Peled, Roberto Zoncu, et al.Cell|August 2, 2015
An Essential Role of the Mitochondrial Electron Transport Chain in Cell Proliferation Is to Enable Aspartate SynthesisKıvanç Birsoy, Tim Wang, Walter W Chen, et al.Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing|December 10, 2021
Image-based profiling: a powerful and challenging new data typeGregory P Way, Hannah Spitzer, Philip Burnham, et al.Pageof 42