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Cell Metabolism|March 2, 2021
CRISPR screens in physiologic medium reveal conditionally essential genes in human cellsNicholas J Rossiter, Kimberly S Huggler, Charles H Adelmann, et al.
Cancer Discovery|March 18, 2014
A diverse array of cancer-associated MTOR mutations are hyperactivating and can predict rapamycin sensitivityBrian C Grabiner, Valentina Nardi, Kıvanc Birsoy, et al.
Proceedings of the National Academy of Sciences of the United States of America|May 11, 2019
Activation of PASK by mTORC1 is required for the onset of the terminal differentiation programChintan K Kikani, Xiaoying Wu, Sarah Fogarty, et al.
Trends in Biotechnology|February 4, 2018
Diagnostic Potential of Imaging Flow CytometryMinh Doan, Ivan Vorobjev, Paul Rees, et al.
Nature Genetics|November 23, 2006
In germ cells of mouse embryonic ovaries, the decision to enter meiosis precedes premeiotic DNA replicationAndrew E Baltus, Douglas B Menke, Yueh-Chiang Hu, et al.
Science (New York, N.Y.)|November 21, 2015
Structural basis for leucine sensing by the Sestrin2-mTORC1 pathwayRobert A Saxton, Kevin E Knockenhauer, Rachel L Wolfson, et al.
Cell|May 19, 2009
DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survivalTimothy R Peterson, Mathieu Laplante, Carson C Thoreen, et al.
Nature|November 19, 2020
MFSD12 mediates the import of cysteine into melanosomes and lysosomesCharles H Adelmann, Anna K Traunbauer, Brandon Chen, et al.
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