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Journal of Molecular Biology|February 2, 2008
An scFv intrabody against the nonamyloid component of alpha-synuclein reduces intracellular aggregation and toxicitySandra M Lynch, Chun Zhou, Anne MesserBehavioral Neuroscience|December 17, 2003
Exploratory activity and fear conditioning abnormalities develop early in R6/2 Huntington's disease transgenic miceValerie J Bolivar, Kevin Manley, Anne MesserJournal of Parkinson'S Disease|November 26, 2013
Can intrabodies serve as neuroprotective therapies for Parkinson's disease? Beginning thoughtsMansi A Bhatt, Anne Messer, Jeffrey H KordowerExpert Opinion on Biological Therapy|August 6, 2009
Developing intrabodies for the therapeutic suppression of neurodegenerative pathologyAnne Messer, Sandra M Lynch, David C ButlerProgress in Neurobiology|November 29, 2011
Engineered antibody therapies to counteract mutant huntingtin and related toxic intracellular proteinsDavid C Butler, Julie A McLear, Anne MesserBiochimica Et Biophysica Acta|September 8, 2014
Antibodies and protein misfolding: From structural research tools to therapeutic strategiesErwin De Genst, Anne Messer, Christopher M DobsonBrain Research|May 22, 2002
The development of behavioral abnormalities in the motor neuron degeneration (mnd) mouseValerie J Bolivar, J Scott Ganus, Anne MesserMabs|August 30, 2012
Fusion to a highly charged proteasomal retargeting sequence increases soluble cytoplasmic expression and efficacy of diverse anti-synuclein intrabodiesShubhada N Joshi, David C Butler, Anne MesserMolecular Therapy : the Journal of the American Society of Gene Therapy|November 27, 2004
A human single-chain Fv intrabody blocks aberrant cellular effects of overexpressed alpha-synucleinChun Zhou, Sharareh Emadi, Michael R Sierks, et al.Journal of Neuropathology and Experimental Neurology|September 15, 2010
Early or late-stage anti-N-terminal Huntingtin intrabody gene therapy reduces pathological features in B6.HDR6/1 miceAbigail Snyder-Keller, Julie A McLear, Tyisha Hathorn, et al.Pageof 5