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Toxicology and Applied Pharmacology|July 23, 2016
Development of a PBPK model of thiocyanate in rats with an extrapolation to humans: A computational study to quantify the mechanism of action of thiocyanate kinetics in thyroidMarie-Emilie Willemin, Annie Lumen
Toxicology and Applied Pharmacology|January 15, 2019
Characterization of the modes of action and dose-response relationship for thiocyanate on the thyroid hormone levels in rats using a computational approachMarie-Emilie Willemin, Annie Lumen
Critical Reviews in Toxicology|June 21, 2017
Thiocyanate: a review and evaluation of the kinetics and the modes of action for thyroid hormone perturbationsMarie-Emilie Willemin, Annie Lumen
Toxicological Sciences : an Official Journal of the Society of Toxicology|March 29, 2013
Evaluation of perturbations in serum thyroid hormones during human pregnancy due to dietary iodide and perchlorate exposure using a biologically based dose-response modelAnnie Lumen, David R Mattie, Jeffrey W Fisher
Biochemical Pharmacology|February 12, 2021
Physiologically based pharmacokinetic (PBPK) modeling of RNAi therapeutics: Opportunities and challengesKiara Fairman, Miao Li, Baitang Ning, et al.
Journal of Environmental Science and Health. Part C, Environmental Carcinogenesis & Ecotoxicology Reviews|March 31, 2012
Extrapolation of hypothalamic-pituitary-thyroid axis perturbations and associated toxicity in rodents to humans: case study with perchlorateJeffrey Fisher, Annie Lumen, John Latendresse, et al.
Clinical Pharmacology and Therapeutics|January 29, 2024
Predicting Clinical Pharmacokinetics/Pharmacodynamics and Impact of Organ Impairment on siRNA-Based Therapeutics Using a Mechanistic Physiologically-Based Pharmacokinetic-Pharmacodynamic ModelAnnie Lumen, Xinwen Zhang, Sandeep Dutta, et al.
International Journal of Environmental Research and Public Health|November 2, 2016
Pediatric Exposures to Ionizing Radiation: Carcinogenic ConsiderationsKristy R Kutanzi, Annie Lumen, Igor Koturbash, et al.
Journal of Thyroid Research|June 28, 2014
The hypothalamic-pituitary-thyroid axis in infants and children: protection from radioiodinesJeffrey Fisher, Xiaoxia Yang, Curtis Harris, et al.
Frontiers in Pharmacology|September 20, 2021
Development, Testing, Parameterisation and Calibration of a Human PBPK Model for the Plasticiser, Di-(2-propylheptyl) Phthalate (DPHP) Using in Silico, in vitro and Human Biomonitoring DataKevin McNally, Craig Sams, Alex Hogg, et al.
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