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Archives of Toxicology|December 10, 2025
Mechanism-based new approach methodologies for in vitro detection of chemical-induced liver steatosisAnouk Verhoeven, Julen Sanz-Serrano, Mathieu Vinken
Expert Opinion on Drug Safety|March 2, 2024
Chemical-induced liver cancer: an adverse outcome pathway perspectiveJulen Sanz-Serrano, Ellen Callewaert, Sybren De Boever, et al.
Toxicology|August 14, 2025
A mechanistically-anchored and human stem cell-based in vitro test battery for assessing liver steatogenic potential of chemicalsAnouk Verhoeven, Alexandra Gatzios, Robim M Rodrigues, et al.
Chemico-Biological Interactions|May 22, 2026
A combined in silico and in vitro new approach methodology for early detection of liver steatogenic chemicalsAnouk Verhoeven, Domenico Gadaleta, Nirseen H K Isbaita, et al.
Archives of Toxicology|May 13, 2024
Investigation of parenteral nutrition-induced hepatotoxicity using human liver spheroid co-culturesMilos Mihajlovic, Sybren De Boever, Andrés Tabernilla, et al.
Frontiers in Toxicology|July 22, 2025
Unlocking liver physiology: comprehensive pathway maps for mechanistic understandingLuiz Ladeira, Anouk Verhoeven, Jonas van Ertvelde, et al.
Life Sciences|July 13, 2026
Human stem cell-derived hepatic cells recapitulate polygenic risk in MASLD development and highlight CD36 as a key mediatorAlexandra Gatzios, Marth Stinckens, Anouk Verhoeven, et al.
Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie|August 16, 2025
Unravelling drug-induced hepatic steatosis: Clinical sub-phenotypes, outcome prediction, and identification of high-concern drugs and hazardous chemical attributesMarta Moreno-Torres, Ernesto López-Pascual, Erika Moro, et al.
Journal of Biomedical Informatics|August 4, 2023
Optimization of an adverse outcome pathway network on chemical-induced cholestasis using an artificial intelligence-assisted data collection and confidence level quantification approachJonas van Ertvelde, Anouk Verhoeven, Amy Maerten, et al.
Toxicology|April 27, 2024
A quantitative weight-of-evidence method for confidence assessment of adverse outcome pathway networks: A case study on chemical-induced liver steatosisAnouk Verhoeven, Jonas van Ertvelde, Joost Boeckmans, et al.
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