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Oncotarget|February 9, 2018
Accelerated bottom-up drug design platform enables the discovery of novel stearoyl-CoA desaturase 1 inhibitors for cancer therapyChristina A von Roemeling, Thomas R Caulfield, Laura Marlow, et al.
ACS Chemical Neuroscience|December 30, 2014
Benzodiazepinone derivatives protect against endoplasmic reticulum stress-mediated cell death in human neuronal cell linesHaixia Zou, Allison S Limpert, Jiwen Zou, et al.
Journal of Medicinal Chemistry|July 15, 2026
Discovery of BBI-355, a Potent, Selective, and Orally Available Checkpoint Kinase 1 Inhibitor for the Treatment of Extrachromosomal DNA Oncogene-Amplified CancersS Todd Meyer, Sudhir Chowdhry, Rachelle J Elsdon, et al.
Journal of Medicinal Chemistry|August 8, 2019
Discovery of β-Arrestin Biased, Orally Bioavailable, and CNS Penetrant Neurotensin Receptor 1 (NTR1) Allosteric ModulatorsAnthony B Pinkerton, Satyamaheshwar Peddibhotla, Fusayo Yamamoto, et al.
Bioorganic & Medicinal Chemistry Letters|December 17, 2013
Imidazole-derived agonists for the neurotensin 1 receptorPaul M Hershberger, Michael P Hedrick, Satyamaheshwar Peddibhotla, et al.
Cancer Research|January 8, 2021
Serine-Threonine Kinase TAO3-Mediated Trafficking of Endosomes Containing the Invadopodia Scaffold TKS5α Promotes Cancer Invasion and Tumor GrowthShinji Iizuka, Manuela Quintavalle, Jose C Navarro, et al.
Bioorganic & Medicinal Chemistry Letters|April 2, 2021
Optimization of a urea-containing series of nicotinamide phosphoribosyltransferase (NAMPT) activatorsAnthony B Pinkerton, E Hampton Sessions, Paul Hershberger, et al.
Plos One|October 13, 2017
Overexpression of tissue-nonspecific alkaline phosphatase (TNAP) in endothelial cells accelerates coronary artery disease in a mouse model of familial hypercholesterolemiaFilippo Romanelli, AnthonyMarco Corbo, Maryam Salehi, et al.
Bioorganic & Medicinal Chemistry Letters|August 31, 2010
Synthesis and SAR of 2-aryl-3-aminomethylquinolines as agonists of the bile acid receptor TGR5Mark R Herbert, Dana L Siegel, Lena Staszewski, et al.
Journal of Medicinal Chemistry|April 29, 2021
Discovery of Orally Bioavailable Purine-Based Inhibitors of the Low-Molecular-Weight Protein Tyrosine PhosphataseStephanie M Stanford, Michael A Diaz, Robert J Ardecky, et al.
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