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Journal of Medicinal Chemistry
|
February 2, 2024
Development of Potent Mcl-1 Inhibitors: Structural Investigations on Macrocycles Originating from a DNA-Encoded Chemical Library Screen
Koen F W Hekking, Sergio Maroto, Kees van Kekem, et al.
ACS Chemical Biology
|
October 19, 2017
Isoform-Selective ATAD2 Chemical Probe with Novel Chemical Structure and Unusual Mode of Action
Amaury E Fernández-Montalván, Markus Berger, Benno Kuropka, et al.
Journal of Medicinal Chemistry
|
March 22, 2023
Discovery of Nanomolar DCAF1 Small Molecule Ligands
Alice Shi Ming Li, Serah Kimani, Brian Wilson, et al.
ACS Medicinal Chemistry Letters
|
November 19, 2025
A Novel Small Molecule Allosteric Inhibitor of IL-17A from a DNA-Encoded Library
Marcos E Milla, Jonathan M Blevitt, Steven D Goldberg, et al.
ACS Medicinal Chemistry Letters
|
November 21, 2017
Correction to "Structure Based Design of Non-Natural Peptidic Macrocyclic Mcl-1 Inhibitors"
Jeffrey W Johannes, Stephanie Bates, Carl Beigie, et al.
ACS Medicinal Chemistry Letters
|
February 16, 2017
Structure Based Design of Non-Natural Peptidic Macrocyclic Mcl-1 Inhibitors
Jeffrey W Johannes, Stephanie Bates, Carl Beigie, et al.
Nature Communications
|
May 6, 2026
A molecular stabiliser of an inhibitory eIF2B-eIF2(αP) complex activates the Integrated Stress Response
Fiona Shilliday, Miguel Gancedo-Rodrigo, Ginto George, et al.
Journal of Medicinal Chemistry
|
April 4, 2024
Discovery of Small Molecule Interleukin 17A Inhibitors with Novel Binding Mode and Stoichiometry: Optimization of DNA-Encoded Chemical Library Hits to In Vivo Active Compounds
Ashley L Ramos, Eric R Goedken, Kristine E Frank, et al.
Journal of Medicinal Chemistry
|
September 27, 2021
Discovery of Novel UDP-<i>N</i>-Acetylglucosamine Acyltransferase (LpxA) Inhibitors with Activity against <i>Pseudomonas aeruginosa</i>
M Dominic Ryan, Alastair L Parkes, David Corbett, et al.
Journal of Medicinal Chemistry
|
November 4, 2024
A Target Class Ligandability Evaluation of WD40 Repeat-Containing Proteins
Suzanne Ackloo, Fengling Li, Magda Szewczyk, et al.
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Showing results (31-40 of 40) with videos related to
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This site can display upto 40 results.
Journal of Medicinal Chemistry
|
February 2, 2024
Development of Potent Mcl-1 Inhibitors: Structural Investigations on Macrocycles Originating from a DNA-Encoded Chemical Library Screen
Koen F W Hekking, Sergio Maroto, Kees van Kekem, et al.
ACS Chemical Biology
|
October 19, 2017
Isoform-Selective ATAD2 Chemical Probe with Novel Chemical Structure and Unusual Mode of Action
Amaury E Fernández-Montalván, Markus Berger, Benno Kuropka, et al.
Journal of Medicinal Chemistry
|
March 22, 2023
Discovery of Nanomolar DCAF1 Small Molecule Ligands
Alice Shi Ming Li, Serah Kimani, Brian Wilson, et al.
ACS Medicinal Chemistry Letters
|
November 19, 2025
A Novel Small Molecule Allosteric Inhibitor of IL-17A from a DNA-Encoded Library
Marcos E Milla, Jonathan M Blevitt, Steven D Goldberg, et al.
ACS Medicinal Chemistry Letters
|
November 21, 2017
Correction to "Structure Based Design of Non-Natural Peptidic Macrocyclic Mcl-1 Inhibitors"
Jeffrey W Johannes, Stephanie Bates, Carl Beigie, et al.
ACS Medicinal Chemistry Letters
|
February 16, 2017
Structure Based Design of Non-Natural Peptidic Macrocyclic Mcl-1 Inhibitors
Jeffrey W Johannes, Stephanie Bates, Carl Beigie, et al.
Nature Communications
|
May 6, 2026
A molecular stabiliser of an inhibitory eIF2B-eIF2(αP) complex activates the Integrated Stress Response
Fiona Shilliday, Miguel Gancedo-Rodrigo, Ginto George, et al.
Journal of Medicinal Chemistry
|
April 4, 2024
Discovery of Small Molecule Interleukin 17A Inhibitors with Novel Binding Mode and Stoichiometry: Optimization of DNA-Encoded Chemical Library Hits to In Vivo Active Compounds
Ashley L Ramos, Eric R Goedken, Kristine E Frank, et al.
Journal of Medicinal Chemistry
|
September 27, 2021
Discovery of Novel UDP-<i>N</i>-Acetylglucosamine Acyltransferase (LpxA) Inhibitors with Activity against <i>Pseudomonas aeruginosa</i>
M Dominic Ryan, Alastair L Parkes, David Corbett, et al.
Journal of Medicinal Chemistry
|
November 4, 2024
A Target Class Ligandability Evaluation of WD40 Repeat-Containing Proteins
Suzanne Ackloo, Fengling Li, Magda Szewczyk, et al.
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