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Current Topics in Medicinal Chemistry|August 5, 2008
Orexin receptor antagonists: medicinal chemistry and therapeutic potentialAnthony J Roecker, Paul J ColemanJournal of Medicinal Chemistry|August 29, 2015
Orexin Receptor Antagonists: New Therapeutic Agents for the Treatment of InsomniaAnthony J Roecker, Christopher D Cox, Paul J ColemanCurrent Topics in Medicinal Chemistry|January 26, 2011
Discovery of dual orexin receptor antagonists (DORAs) for the treatment of insomniaPaul J Coleman, Christopher D Cox, Anthony J RoeckerProgress in Brain Research|July 21, 2012
Orexin receptors as therapeutic drug targetsAnthony L Gotter, Anthony J Roecker, Richard Hargreaves, et al.Organic Letters|January 29, 2020
Continuous Flow-Enabled Synthesis of Bench-Stable Bicyclo[1.1.1]pentane Trifluoroborate Salts and Their Utilization in Metallaphotoredox Cross-CouplingsMichael D VanHeyst, Ji Qi, Anthony J Roecker, et al.Journal of Medicinal Chemistry|February 22, 2022
Building a Culture of Medicinal Chemistry Knowledge SharingDouglas C Beshore, Andrew M Haidle, Ashok Arasappan, et al.Behavioural Brain Research|April 22, 2014
Selective orexin 2 receptor antagonism blocks cue-induced reinstatement, but not nicotine self-administration or nicotine-induced reinstatementJason M Uslaner, Christopher J Winrow, Anthony L Gotter, et al.Journal of Neurochemistry|April 27, 2017
The dual orexin receptor antagonist, DORA-22, lowers histamine levels in the lateral hypothalamus and prefrontal cortex without lowering hippocampal acetylcholineLihang Yao, Andres D Ramirez, Anthony J Roecker, et al.Nature Structural & Molecular Biology|March 8, 2016
Structure and ligand-binding mechanism of the human OX1 and OX2 orexin receptorsJie Yin, Kerim Babaoglu, Chad A Brautigam, et al.Bioorganic & Medicinal Chemistry Letters|April 8, 2014
Discovery of dual orexin receptor antagonists with rat sleep efficacy enabled by expansion of the acetonitrile-assisted/diphosgene-mediated 2,4-dichloropyrimidine synthesisAnthony J Roecker, Swati P Mercer, C Meacham Harrell, et al.Pageof 3