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Cancer Research|February 8, 2005
Identification of a novel small-molecule inhibitor of the hypoxia-inducible factor 1 pathwayChalet Tan, Rita G de Noronha, Anthony J Roecker, et al.Neuropharmacology|July 15, 2009
Orexin receptor antagonism prevents transcriptional and behavioral plasticity resulting from stimulant exposureChristopher J Winrow, Keith Q Tanis, Duane R Reiss, et al.Bioorganic & Medicinal Chemistry Letters|July 9, 2010
Discovery of 3,9-diazabicyclo[4.2.1]nonanes as potent dual orexin receptor antagonists with sleep-promoting activity in the ratPaul J Coleman, John D Schreier, Anthony J Roecker, et al.Bioorganic & Medicinal Chemistry Letters|January 22, 2008
Proline bis-amides as potent dual orexin receptor antagonistsJeffrey M Bergman, Anthony J Roecker, Swati P Mercer, et al.Bioorganic & Medicinal Chemistry Letters|November 13, 2013
Discovery of 2,5-diarylnicotinamides as selective orexin-2 receptor antagonists (2-SORAs)Swati P Mercer, Anthony J Roecker, Susan Garson, et al.Bioorganic & Medicinal Chemistry Letters|January 24, 2015
Discovery of diazepane amide DORAs and 2-SORAs enabled by exploration of isosteric quinazoline replacementsAnthony J Roecker, Swati P Mercer, Jeffrey M Bergman, et al.ACS Medicinal Chemistry Letters|June 18, 2021
Discovery of Arylsulfonamide Nav1.7 Inhibitors: IVIVC, MPO Methods, and Optimization of Selectivity ProfileAnthony J Roecker, Mark E Layton, Joseph E Pero, et al.Scientific Reports|June 4, 2016
Orexin 2 Receptor Antagonism is Sufficient to Promote NREM and REM Sleep from Mouse to ManAnthony L Gotter, Mark S Forman, Charles M Harrell, et al.Bioorganic & Medicinal Chemistry Letters|September 4, 2007
Kinesin spindle protein (KSP) inhibitors. Part 8: Design and synthesis of 1,4-diaryl-4,5-dihydropyrazoles as potent inhibitors of the mitotic kinesin KSPAnthony J Roecker, Paul J Coleman, Swati P Mercer, et al.Channels (Austin, Tex.)|October 14, 2022
Association of respiratory failure with inhibition of NaV1.6 in the phrenic nerveRebecca M Klein, Mark E Layton, Hillary Regan, et al.Pageof 3