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The Journal of Biological Chemistry
|
August 11, 2023
1-deoxy-D-xylulose-5-phosphate synthase from Pseudomonas aeruginosa and Klebsiella pneumoniae reveals conformational changes upon cofactor binding
Rawia Hamid, Sebastian Adam, Antoine Lacour, et al.
Structure (London, England : 1993)
|
November 7, 2024
IspE kinase as an anti-infective target: Role of a hydrophobic pocket in inhibitor binding
Rawia Hamid, Danica J Walsh, Eleonora Diamanti, et al.
Chemmedchem
|
December 17, 2021
Targeting the IspD Enzyme in the MEP Pathway: Identification of a Novel Fragment Class
Eleonora Diamanti, Mostafa M Hamed, Antoine Lacour, et al.
Bioorganic Chemistry
|
August 22, 2025
Targeting isoprenoid-precursor biosynthesis in Klebsiella pneumoniae: Design, synthesis and evaluation of 1-deoxy-D-xylulose 5-phosphate synthase (DXPS) inhibitors
Sidra Eisa, Antoine Lacour, Sandra Johannsen, et al.
Research Square
|
April 17, 2026
X-ray Co-crystal Structure of a Novel Pseudomonas aeruginosa DXPS Inhibitor Reveals an Unusual Allosteric Binding Pocket
Anna Hirsch, Antoine Lacour, Rawia Hamid, et al.
ACS Medicinal Chemistry Letters
|
April 15, 2026
Identification of Natural-Product Inhibitors of the 2<i>C</i>‑Methyl‑d‑erythritol 4‑Phosphate Pathway
Eleonora Diamanti, Alaa Alhayek, Antoine Lacour, et al.
ACS Infectious Diseases
|
November 20, 2024
Studying Target-Engagement of Anti-Infectives by Solvent-Induced Protein Precipitation and Quantitative Mass Spectrometry
Lorenzo Bizzarri, Dominik Steinbrunn, Thibaut Quennesson, et al.
Plos Pathogens
|
July 17, 2023
NRF2 activators inhibit influenza A virus replication by interfering with nucleo-cytoplasmic export of viral RNPs in an NRF2-independent manner
Fakhar H Waqas, Mahmoud Shehata, Walid A M Elgaher, et al.
ACS Omega
|
November 11, 2024
Targeting the <i>Plasmodium falciparum</i> IspE Enzyme
Eleonora Diamanti, Annina M Steinbach, Lais P de Carvalho, et al.
ACS Infectious Diseases
|
February 17, 2024
High Target Homology Does Not Guarantee Inhibition: Aminothiazoles Emerge as Inhibitors of <i>Plasmodium falciparum</i>
Sandra Johannsen, Robin M Gierse, Arne Krüger, et al.
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Showing results (1-10 of 10) with videos related to
Sort By:
Page
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The Journal of Biological Chemistry
|
August 11, 2023
1-deoxy-D-xylulose-5-phosphate synthase from Pseudomonas aeruginosa and Klebsiella pneumoniae reveals conformational changes upon cofactor binding
Rawia Hamid, Sebastian Adam, Antoine Lacour, et al.
Structure (London, England : 1993)
|
November 7, 2024
IspE kinase as an anti-infective target: Role of a hydrophobic pocket in inhibitor binding
Rawia Hamid, Danica J Walsh, Eleonora Diamanti, et al.
Chemmedchem
|
December 17, 2021
Targeting the IspD Enzyme in the MEP Pathway: Identification of a Novel Fragment Class
Eleonora Diamanti, Mostafa M Hamed, Antoine Lacour, et al.
Bioorganic Chemistry
|
August 22, 2025
Targeting isoprenoid-precursor biosynthesis in Klebsiella pneumoniae: Design, synthesis and evaluation of 1-deoxy-D-xylulose 5-phosphate synthase (DXPS) inhibitors
Sidra Eisa, Antoine Lacour, Sandra Johannsen, et al.
Research Square
|
April 17, 2026
X-ray Co-crystal Structure of a Novel Pseudomonas aeruginosa DXPS Inhibitor Reveals an Unusual Allosteric Binding Pocket
Anna Hirsch, Antoine Lacour, Rawia Hamid, et al.
ACS Medicinal Chemistry Letters
|
April 15, 2026
Identification of Natural-Product Inhibitors of the 2<i>C</i>‑Methyl‑d‑erythritol 4‑Phosphate Pathway
Eleonora Diamanti, Alaa Alhayek, Antoine Lacour, et al.
ACS Infectious Diseases
|
November 20, 2024
Studying Target-Engagement of Anti-Infectives by Solvent-Induced Protein Precipitation and Quantitative Mass Spectrometry
Lorenzo Bizzarri, Dominik Steinbrunn, Thibaut Quennesson, et al.
Plos Pathogens
|
July 17, 2023
NRF2 activators inhibit influenza A virus replication by interfering with nucleo-cytoplasmic export of viral RNPs in an NRF2-independent manner
Fakhar H Waqas, Mahmoud Shehata, Walid A M Elgaher, et al.
ACS Omega
|
November 11, 2024
Targeting the <i>Plasmodium falciparum</i> IspE Enzyme
Eleonora Diamanti, Annina M Steinbach, Lais P de Carvalho, et al.
ACS Infectious Diseases
|
February 17, 2024
High Target Homology Does Not Guarantee Inhibition: Aminothiazoles Emerge as Inhibitors of <i>Plasmodium falciparum</i>
Sandra Johannsen, Robin M Gierse, Arne Krüger, et al.
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