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Molecular Therapy. Nucleic Acids|November 4, 2024
Mechanistic insights into ASO-RNA complexation: Advancing antisense oligonucleotide design strategiesJohanna Hörberg, Antonio Carlesso, Anna Reymer
RSC Advances|May 6, 2022
Deciphering the selectivity of inhibitor MKC9989 towards residue K907 in IRE1α; a multiscale in silico approachSayyed Jalil Mahdizadeh, Antonio Carlesso, Leif A Eriksson
Scientific Reports|October 16, 2020
New insights on human IRE1 tetramer structures based on molecular modelingAntonio Carlesso, Johanna Hörberg, Anna Reymer, et al.
NAR Genomics and Bioinformatics|May 27, 2024
Structural dynamics of therapeutic nucleic acids with phosphorothioate backbone modificationsAntonio Carlesso, Johanna Hörberg, Giuseppe Deganutti, et al.
Journal of Chemical Information and Modeling|August 12, 2022
QM/MM Well-Tempered Metadynamics Study of the Mechanism of XBP1 mRNA Cleavage by Inositol Requiring Enzyme 1α RNaseSayyed Jalil Mahdizadeh, Emil Pålsson, Antonio Carlesso, et al.
International Journal of Molecular Sciences|November 9, 2019
Effect of Kinase Inhibiting RNase Attenuator (KIRA) Compounds on the Formation of Face-to-Face Dimers of Inositol-Requiring Enzyme 1: Insights from Computational ModelingAntonio Carlesso, Chetan Chintha, Adrienne M Gorman, et al.
ACS Omega|November 10, 2018
Binding Analysis of the Inositol-Requiring Enzyme 1 Kinase DomainAntonio Carlesso, Chetan Chintha, Adrienne M Gorman, et al.
RSC Advances|May 13, 2022
Molecular modeling provides a structural basis for PERK inhibitor selectivity towards RIPK1Chetan Chintha, Antonio Carlesso, Adrienne M Gorman, et al.
Trends in Cancer|August 31, 2020
Pharmacological Targeting of IRE1 in CancerDiana Pelizzari Raymundo, Dimitrios Doultsinos, Xavier Guillory, et al.
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