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Acta Crystallographica. Section D, Biological Crystallography|July 10, 2014
Structural basis of the transactivation deficiency of the human PPARγ F360L mutant associated with familial partial lipodystrophyClorinda Lori, Alessandra Pasquo, Roberta Montanari, et al.Journal of Medicinal Chemistry|September 11, 2018
Identification of the First PPARα/γ Dual Agonist Able To Bind to Canonical and Alternative Sites of PPARγ and To Inhibit Its Cdk5-Mediated PhosphorylationAntonio Laghezza, Luca Piemontese, Carmen Cerchia, et al.European Journal of Medicinal Chemistry|December 13, 2021
Development of novel phenoxyalkylpiperidines as high-affinity Sigma-1 (σ1) receptor ligands with potent anti-amnesic effectFrancesca S Abatematteo, Philip D Mosier, Mauro Niso, et al.The Journal of Pharmacology and Experimental Therapeutics|October 27, 2011
Structural nucleotide analogs are potent activators/inhibitors of pancreatic β cell KATP channels: an emerging mechanism supporting their use as antidiabetic drugsDomenico Tricarico, Jean-François Rolland, Gianluigi Cannone, et al.Scientific Reports|July 20, 2017
Betulinic acid is a PPARγ antagonist that improves glucose uptake, promotes osteogenesis and inhibits adipogenesisGloria Brusotti, Roberta Montanari, Davide Capelli, et al.Journal of Enzyme Inhibition and Medicinal Chemistry|August 25, 2016
Catechol-based matrix metalloproteinase inhibitors with additional antioxidative activityMarilena Tauro, Antonio Laghezza, Fulvio Loiodice, et al.Biomolecules|January 20, 2021
Derivatives of Tenuazonic Acid as Potential New Multi-Target Anti-Alzheimer's Disease AgentsViviana Poliseno, Sílvia Chaves, Leonardo Brunetti, et al.Pharmaceuticals (Basel, Switzerland)|June 5, 2020
Bone-Seeking Matrix Metalloproteinase Inhibitors for the Treatment of Skeletal MalignancyAntonio Laghezza, Luca Piemontese, Leonardo Brunetti, et al.Journal of Medicinal Chemistry|September 25, 2009
New 2-aryloxy-3-phenyl-propanoic acids as peroxisome proliferator-activated receptors alpha/gamma dual agonists with improved potency and reduced adverse effects on skeletal muscle functionGiuseppe Fracchiolla, Antonio Laghezza, Luca Piemontese, et al.Journal of Medicinal Chemistry|August 19, 2005
Synthesis, biological evaluation, and molecular modeling investigation of new chiral fibrates with PPARalpha and PPARgamma agonist activityAlessandra Pinelli, Cristina Godio, Antonio Laghezza, et al.Pageof 8