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Cell Metabolism|September 3, 2009
TGR5-mediated bile acid sensing controls glucose homeostasisCharles Thomas, Antimo Gioiello, Lilia Noriega, et al.
European Journal of Medicinal Chemistry|August 1, 2026
Targeting oxysterol-binding protein (OSBP) as a novel strategy to inhibit herpes simplex virus 2 (HSV-2) replication: First structure-activity relationship study of antiviral cholenamide derivativesAndrea Civra, Fatima Nigro, Domiziana Porporato, et al.
Microorganisms|July 27, 2022
The Combination of Molnupiravir with Nirmatrelvir or GC376 Has a Synergic Role in the Inhibition of SARS-CoV-2 Replication In VitroAnna Gidari, Samuele Sabbatini, Elisabetta Schiaroli, et al.
Frontiers in Immunology|November 20, 2025
Adverse pro-tumorigenic effects of IDO1 catalytic inhibitors mediated by the non-enzymatic function of IDO1 in tumor cellsSofia Rossini, Sara Ambrosino, Claudia Volpi, et al.
Communications Chemistry|September 24, 2025
Ligand-induced conformations and dynamic allosteric motions of IDO1 affecting the recruitment of a protein signaling partnerAlice Coletti, Elisa Bianconi, Sofia Rossini, et al.
Bioorganic & Medicinal Chemistry|May 9, 2012
Pyrazole[3,4-e][1,4]thiazepin-7-one derivatives as a novel class of Farnesoid X Receptor (FXR) agonistsMaura Marinozzi, Andrea Carotti, Emanuele Sansone, et al.
European Journal of Medicinal Chemistry|October 10, 2014
Scaffold hopping approach on the route to selective tankyrase inhibitorsParide Liscio, Andrea Carotti, Stefania Asciutti, et al.
ACS Medicinal Chemistry Letters|June 6, 2014
Probing the Binding Site of Bile Acids in TGR5Antonio Macchiarulo, Antimo Gioiello, Charles Thomas, et al.
Journal of Autoimmunity|July 2, 2020
A novel mutation of indoleamine 2,3-dioxygenase 1 causes a rapid proteasomal degradation and compromises protein functionGiada Mondanelli, Valeria Di Battista, Fabrizia Pellanera, et al.
The Journal of Biological Chemistry|December 21, 2016
Signal Transducer and Activator of Transcription 1 Plays a Pivotal Role in RET/PTC3 Oncogene-induced Expression of Indoleamine 2,3-Dioxygenase 1Sonia Moretti, Elisa Menicali, Nicole Nucci, et al.
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