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European Journal of Medicinal Chemistry|August 17, 2024
Optimization of potent, broad-spectrum, and specific anti-influenza compounds targeting RNA polymerase PA-PB1 heterodimerizationAnna Bonomini, Tommaso Felicetti, Martina Pacetti, et al.Future Medicinal Chemistry|July 26, 2018
Lead optimization-hit expansion of new asymmetrical pyridinium/quinolinium compounds as choline kinase α1 inhibitorsGianluca Rubbini, Ana Begoña Buades-Martín, María Kimatrai-Salvador, et al.International Journal of Molecular Sciences|April 13, 2023
Stabilization of the Dimeric State of SARS-CoV-2 Main Protease by GC376 and NirmatrelvirAlessandro Paciaroni, Valeria Libera, Francesca Ripanti, et al.Angewandte Chemie (International Ed. in English)|June 5, 2023
Combining Solid-State NMR with Structural and Biophysical Techniques to Design Challenging Protein-Drug ConjugatesLinda Cerofolini, Kristian Vasa, Elisa Bianconi, et al.Cancer Research|September 12, 2015
Targeting the MDM2/MDM4 interaction interface as a promising approach for p53 reactivation therapyMarsha Pellegrino, Francesca Mancini, Rossella Lucà, et al.Chemico-Biological Interactions|March 20, 2021
Taxifolin and gastro-adhesive microparticles containing taxifolin promotes gastric healing in vivo, inhibits Helicobacter pylori in vitro and proton pump reversibly in silicoFernanda Cristina Stenger Moura, Valdir Cechinel-Filho, Francesco Antonio Greco, et al.The Journal of Clinical Endocrinology and Metabolism|February 13, 2014
Indoleamine 2,3-dioxygenase 1 (IDO1) is up-regulated in thyroid carcinoma and drives the development of an immunosuppressant tumor microenvironmentSonia Moretti, Elisa Menicali, Pasquale Voce, et al.Immunity|February 19, 2017
A Relay Pathway between Arginine and Tryptophan Metabolism Confers Immunosuppressive Properties on Dendritic CellsGiada Mondanelli, Roberta Bianchi, Maria Teresa Pallotta, et al.Journal of Medicinal Chemistry|September 2, 2008
Adamantyl-substituted retinoid-derived molecules that interact with the orphan nuclear receptor small heterodimer partner: effects of replacing the 1-adamantyl or hydroxyl group on inhibition of cancer cell growth, induction of cancer cell apoptosis, and inhibition of SRC homology 2 domain-containing protein tyrosine phosphatase-2 activityMarcia I Dawson, Zebin Xia, Tao Jiang, et al.Proceedings of the National Academy of Sciences of the United States of America|February 7, 2020
Positive allosteric modulation of indoleamine 2,3-dioxygenase 1 restrains neuroinflammationGiada Mondanelli, Alice Coletti, Francesco Antonio Greco, et al.Pageof 16