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The Journal of Biological Chemistry|December 10, 2002
APH-1 interacts with mature and immature forms of presenilins and nicastrin and may play a role in maturation of presenilin.nicastrin complexesYongjun Gu, Fusheng Chen, Nobuo Sanjo, et al.
Brain Communications|November 11, 2021
Viral alpha-synuclein knockdown prevents spreading synucleinopathySindhu Menon, Rikke H Kofoed, Fadl Nabbouh, et al.
The Journal of Biological Chemistry|August 5, 2005
Wild-type PINK1 prevents basal and induced neuronal apoptosis, a protective effect abrogated by Parkinson disease-related mutationsAgnes Petit, Toshitaka Kawarai, Erwan Paitel, et al.
Molecular & Cellular Oncology|June 17, 2016
PINK1 deficiency enhances autophagy and mitophagy inductionRubén Gómez-Sánchez, Sokhna M S Yakhine-Diop, José M Bravo-San Pedro, et al.
The Journal of Biological Chemistry|March 21, 2003
Presenilin 1 and presenilin 2 have differential effects on the stability and maturation of nicastrin in Mammalian brainFusheng Chen, Anurag Tandon, Nobuo Sanjo, et al.
The Journal of Biological Chemistry|May 29, 2002
Mature glycosylation and trafficking of nicastrin modulate its binding to presenilinsDun-Sheng Yang, Anurag Tandon, Fusheng Chen, et al.
Nature|April 28, 2006
TMP21 is a presenilin complex component that modulates gamma-secretase but not epsilon-secretase activityFusheng Chen, Hiroshi Hasegawa, Gerold Schmitt-Ulms, et al.
Nature Communications|February 21, 2018
C-terminal calcium binding of α-synuclein modulates synaptic vesicle interactionJanin Lautenschläger, Amberley D Stephens, Giuliana Fusco, et al.
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