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Chemical Science|May 5, 2022
Enzymology of standalone elongating ketosynthasesAochiu Chen, Ziran Jiang, Michael D BurkartNatural Product Reports|July 27, 2018
Type II fatty acid and polyketide synthases: deciphering protein-protein and protein-substrate interactionsAochiu Chen, Rebecca N Re, Michael D BurkartBiochemistry|December 1, 2023
Substrate Sequestration and Chain Flipping in Human Mitochondrial Acyl Carrier ProteinYixing Suo, Aochiu Chen, James J La Clair, et al.Nature Chemical Biology|May 6, 2020
Structural basis for selectivity in a highly reducing type II polyketide synthaseDanyao Du, Yohei Katsuyama, Masanobu Horiuchi, et al.The AAPS Journal|April 7, 2026
Predicting Aberrant Fc-fusion Protein Pharmacokinetics from In Silico Structural Properties and Physiologically Based Pharmacokinetic (PBPK) ModelingDanilo Tomasoni, Alessio Paris, Roberto Visintainer, et al.ACS Catalysis|October 3, 2022
Structure and mechanistic analyses of the gating mechanism of elongating ketosynthasesJeffrey T Mindrebo, Aochiu Chen, Woojoo E Kim, et al.Chemical Science|October 13, 2023
Masked cerulenin enables a dual-site selective protein crosslinkZiran Jiang, Aochiu Chen, Jeffrey Chen, et al.Acta Crystallographica. Section D, Structural Biology|September 1, 2022
Mechanism-based cross-linking probes capture the Escherichia coli ketosynthase FabB in conformationally distinct catalytic statesAochiu Chen, Jeffrey T Mindrebo, Tony D Davis, et al.Journal of the American Chemical Society|July 9, 2024
Cryptic Cerulenin Rearrangement in Ketosynthase Covalent InhibitionZiran Jiang, Jeffrey A Chen, Osama G Mohamed, et al.Nature Communications|April 9, 2020
Gating mechanism of elongating β-ketoacyl-ACP synthasesJeffrey T Mindrebo, Ashay Patel, Woojoo E Kim, et al.Pageof 2