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Cell Chemical Biology|December 7, 2023
Subtype-selective prenylated isoflavonoids disrupt regulatory drivers of MYCN-amplified cancersMichael E Stokes, Alessandro Vasciaveo, Jonnell Candice Small, et al.Bioorganic & Medicinal Chemistry Letters|September 30, 2004
Synthesis and activity of novel analogs of hemiasterlin as inhibitors of tubulin polymerization: modification of the A segmentAyako Yamashita, Emily B Norton, Joshua A Kaplan, et al.Nature Communications|April 2, 2021
Lead compounds for the development of SARS-CoV-2 3CL protease inhibitorsSho Iketani, Farhad Forouhar, Hengrui Liu, et al.Biorxiv : the Preprint Server for Biology|August 15, 2020
Lead compounds for the development of SARS-CoV-2 3CL protease inhibitorsSho Iketani, Farhad Forouhar, Hengrui Liu, et al.Journal of Medicinal Chemistry|November 26, 2009
Hybrid inhibitors of phosphatidylinositol 3-kinase (PI3K) and the mammalian target of rapamycin (mTOR): design, synthesis, and superior antitumor activity of novel wortmannin-rapamycin conjugatesSemiramis Ayral-Kaloustian, Jianxin Gu, Judy Lucas, et al.Biochemistry|May 4, 2005
Two photoaffinity analogues of the tripeptide, hemiasterlin, exclusively label alpha-tubulinMaria Nunes, Joshua Kaplan, Joseph Wooters, et al.Molecular Cancer Therapeutics|October 16, 2004
Cells resistant to HTI-286 do not overexpress P-glycoprotein but have reduced drug accumulation and a point mutation in alpha-tubulinFrank Loganzo, Malathi Hari, Tami Annable, et al.Journal of Medicinal Chemistry|February 17, 2006
Pegylated wortmannin and 17-hydroxywortmannin conjugates as phosphoinositide 3-kinase inhibitors active in human tumor xenograft modelsTianmin Zhu, Jianxin Gu, Ker Yu, et al.Journal of Medicinal Chemistry|November 30, 2004
Synthesis and structure-activity relationships of 4-alkynyloxy phenyl sulfanyl, sulfinyl, and sulfonyl alkyl hydroxamates as tumor necrosis factor-alpha converting enzyme and matrix metalloproteinase inhibitorsAranapakam M Venkatesan, Jamie M Davis, George T Grosu, et al.Nature Communications|January 3, 2025
Development of small molecule non-covalent coronavirus 3CL protease inhibitors from DNA-encoded chemical library screeningHengrui Liu, Arie Zask, Farhad Forouhar, et al.Pageof 6