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Nature Communications|November 24, 2017
Structural insights into substrate and inhibitor binding sites in human indoleamine 2,3-dioxygenase 1Ariel Lewis-Ballester, Khoa N Pham, Dipanwita Batabyal, et al.
Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry|April 3, 2010
The first step of the dioxygenation reaction carried out by tryptophan dioxygenase and indoleamine 2,3-dioxygenase as revealed by quantum mechanical/molecular mechanical studiesLuciana Capece, Ariel Lewis-Ballester, Dipanwita Batabyal, et al.
Journal of Medicinal Chemistry|August 6, 2024
Structural Insights into Protein-Inhibitor Interactions in Human Tryptophan DioxygenaseZachary Geeraerts, Izumi Ishigami, Ariel Lewis-Ballester, et al.
Proceedings of the National Academy of Sciences of the United States of America|October 7, 2009
Evidence for a ferryl intermediate in a heme-based dioxygenaseAriel Lewis-Ballester, Dipanwita Batabyal, Tsuyoshi Egawa, et al.
European Journal of Medicinal Chemistry|November 24, 2018
Diaryl hydroxylamines as pan or dual inhibitors of indoleamine 2,3-dioxygenase-1, indoleamine 2,3-dioxygenase-2 and tryptophan dioxygenaseMaria Winters, James B DuHadaway, Khoa N Pham, et al.
European Journal of Medicinal Chemistry|December 31, 2015
O-alkylhydroxylamines as rationally-designed mechanism-based inhibitors of indoleamine 2,3-dioxygenase-1William P Malachowski, Maria Winters, James B DuHadaway, et al.
Scientific Reports|October 21, 2016
Molecular basis for catalysis and substrate-mediated cellular stabilization of human tryptophan 2,3-dioxygenaseAriel Lewis-Ballester, Farhad Forouhar, Sung-Mi Kim, et al.
Nature Microbiology|November 4, 2025
Structural and mechanistic insights into herpesvirus helicase-primase and its therapeutic inhibitorsQing Yao, Alexandre Mercier, Arabinda Nayak, et al.
Proceedings of the National Academy of Sciences of the United States of America|February 28, 2019
Snapshot of an oxygen intermediate in the catalytic reaction of cytochrome <i>c</i> oxidaseIzumi Ishigami, Ariel Lewis-Ballester, Austin Echelmeier, et al.
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