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Microbiology Spectrum|February 20, 2024
Investigating inhibitors of 1-deoxy-d-xylulose 5-phosphate synthase in a mouse model of UTIEric C Chen, Rachel L Shapiro, Arindom Pal, et al.Biochemical Pharmacology|October 22, 2021
Inhibition of neutral sphingomyelinase 2 reduces extracellular vesicle release from neurons, oligodendrocytes, and activated microglial cells following acute brain injuryCarolyn Tallon, Silvia Picciolini, Seung-Wan Yoo, et al.Molecular Pharmaceutics|May 29, 2019
Hydrophilic Small Molecules That Harness Transthyretin To Enhance the Safety and Efficacy of Targeted Chemotherapeutic AgentsArindom Pal, Wabel Albusairi, Fang Liu, et al.European Journal of Medicinal Chemistry|August 3, 2023
Neutral sphingomyelinase 2 inhibitors based on the pyrazolo[1,5-a]pyrimidin-3-amine scaffoldKaterina Novotna, Ajit G Thomas, Ondrej Stepanek, et al.Current Drug Metabolism|September 7, 2021
Glutamine Antagonist GA-607 Causes a Dramatic Accumulation of FGAR which can be used to Monitor Target EngagementJesse Alt, Sadakatali S Gori, Kathryn M Lemberg, et al.Pharmaceutical Research|June 4, 2025
Assessing Impact of Food on Oral Drug Bioequivalence Supporting ICH M13 A with the Advancements of Physiologically Based Pharmacokinetic ModelingArindom Pal, Khondoker Alam, Ethan Stier, et al.Nature Chemical Biology|September 8, 2015
A biomimetic approach for enhancing the in vivo half-life of peptidesSravan C Penchala, Mark R Miller, Arindom Pal, et al.Pharmaceutics|October 27, 2022
Dendrimer-Conjugated nSMase2 Inhibitor Reduces Tau Propagation in MiceCarolyn Tallon, Benjamin J Bell, Anjali Sharma, et al.Journal of Medicinal Chemistry|August 23, 2018
Enthalpy-Driven Stabilization of Transthyretin by AG10 Mimics a Naturally Occurring Genetic Variant That Protects from Transthyretin AmyloidosisMark Miller, Arindom Pal, Wabel Albusairi, et al.Research Square|July 28, 2023
Inhibiting tau-induced elevated nSMase2 activity and ceramides is therapeutic in murine Alzheimer's diseaseCarolyn Tallon, Benjamin J Bell, Medhinee M Malvankar, et al.Pageof 3