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Journal of Medicinal Chemistry
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October 24, 2022
Overcoming Preclinical Safety Obstacles to Discover (<i>S</i>)-<i>N</i>-((1,2,3,5,6,7-Hexahydro-<i>s</i>-indacen-4-yl)carbamoyl)-6-(methylamino)-6,7-dihydro-5<i>H</i>-pyrazolo[5,1-<i>b</i>][1,3]oxazine-3-sulfonamide (GDC-2394): A Potent and Selective NLRP3 Inhibitor
Christopher McBride, Lynnie Trzoss, Davide Povero, et al.
JCI Insight
|
April 14, 2017
Btk-specific inhibition blocks pathogenic plasma cell signatures and myeloid cell-associated damage in IFN<b>α</b>-driven lupus nephritis
Arna Katewa, Yugang Wang, Jason A Hackney, et al.
ACS Medicinal Chemistry Letters
|
June 20, 2017
Discovery of Potent and Selective Tricyclic Inhibitors of Bruton's Tyrosine Kinase with Improved Druglike Properties
Xiaojing Wang, James Barbosa, Peter Blomgren, et al.
Science Signaling
|
June 4, 2020
The kinase IRAK4 promotes endosomal TLR and immune complex signaling in B cells and plasmacytoid dendritic cells
Cesar A Corzo, Eugene Varfolomeev, A Francesca Setiadi, et al.
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Search research articles
Search
Showing results (11-20 of 14) with videos related to
Sort By:
Page
of 2
You have reached the last page of results.
This site can display upto 14 results.
Journal of Medicinal Chemistry
|
October 24, 2022
Overcoming Preclinical Safety Obstacles to Discover (<i>S</i>)-<i>N</i>-((1,2,3,5,6,7-Hexahydro-<i>s</i>-indacen-4-yl)carbamoyl)-6-(methylamino)-6,7-dihydro-5<i>H</i>-pyrazolo[5,1-<i>b</i>][1,3]oxazine-3-sulfonamide (GDC-2394): A Potent and Selective NLRP3 Inhibitor
Christopher McBride, Lynnie Trzoss, Davide Povero, et al.
JCI Insight
|
April 14, 2017
Btk-specific inhibition blocks pathogenic plasma cell signatures and myeloid cell-associated damage in IFN<b>α</b>-driven lupus nephritis
Arna Katewa, Yugang Wang, Jason A Hackney, et al.
ACS Medicinal Chemistry Letters
|
June 20, 2017
Discovery of Potent and Selective Tricyclic Inhibitors of Bruton's Tyrosine Kinase with Improved Druglike Properties
Xiaojing Wang, James Barbosa, Peter Blomgren, et al.
Science Signaling
|
June 4, 2020
The kinase IRAK4 promotes endosomal TLR and immune complex signaling in B cells and plasmacytoid dendritic cells
Cesar A Corzo, Eugene Varfolomeev, A Francesca Setiadi, et al.
Page
of 2