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Biorxiv : the Preprint Server for Biology|November 24, 2025
Shared Binding Site but Divergent Resistance Profiles Uncover Novel Resistance Mechanisms in Plasmodium HSP90 InhibitorsFu-Hsuan Ko, Amanda K Lukens, Mariana Laureano de Souza, et al.Nature Chemical Biology|May 6, 2008
Gene expression signatures and small-molecule compounds link a protein kinase to Plasmodium falciparum motilityNobutaka Kato, Tomoyo Sakata, Ghislain Breton, et al.Molecular Therapy. Nucleic Acids|October 8, 2024
Inhibition of SARS-CoV-2 growth in the lungs of mice by a peptide-conjugated morpholino oligomer targeting viral RNAAlexandra Sakai, Gagandeep Singh, Mahsa Khoshbakht, et al.Cell Reports|July 6, 2026
Plasmodium falciparum HSP90 inhibitors show divergent resistance despite a shared ATP-binding siteFu-Hsuan Ko, Amanda K Lukens, Mariana Laureano de Souza, et al.ACS Chemical Biology|April 17, 2012
A high-throughput screen to identify inhibitors of ATP homeostasis in non-replicating Mycobacterium tuberculosisPuiying A Mak, Srinivasa P S Rao, Mai Ping Tan, et al.PNAS Nexus|March 26, 2024
A small molecule MST1/2 inhibitor accelerates murine liver regeneration with improved survival in models of steatohepatitisRyan Watkins, Ana Gamo, Seung Hyuk Choi, et al.Nature Communications|November 26, 2014
Pyrazoleamide compounds are potent antimalarials that target Na+ homeostasis in intraerythrocytic Plasmodium falciparumAkhil B Vaidya, Joanne M Morrisey, Zhongsheng Zhang, et al.Science (New York, N.Y.)|November 19, 2011
Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discoveryStephan Meister, David M Plouffe, Kelli L Kuhen, et al.Nature Communications|October 27, 2010
A chemical genetic screen in Mycobacterium tuberculosis identifies carbon-source-dependent growth inhibitors devoid of in vivo efficacyKevin Pethe, Patricia C Sequeira, Sanjay Agarwalla, et al.Pageof 10