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Journal of Neurochemistry|November 3, 2010
GAD65 is essential for synthesis of GABA destined for tonic inhibition regulating epileptiform activityAnne B Walls, Linn Hege Nilsen, Elvar M Eyjolfsson, et al.Journal of Medicinal Chemistry|May 16, 2003
Design, synthesis, and pharmacology of a highly subtype-selective GluR1/2 agonist, (RS)-2-amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)propionic acid (Cl-HIBO)Esben J Bjerrum, Anders S Kristensen, Darryl S Pickering, et al.Journal of Neurochemistry|March 15, 2011
Synthesis of neurotransmitter GABA via the neuronal tricarboxylic acid cycle is elevated in rats with liver cirrhosis consistent with a high GABAergic tone in chronic hepatic encephalopathyRenata Leke, Lasse K Bak, Peter Iversen, et al.Biochemical Pharmacology|June 25, 2013
Discovery of a subtype selective inhibitor of the human betaine/GABA transporter 1 (BGT-1) with a non-competitive pharmacological profileBolette Kragholm, Trine Kvist, Karsten K Madsen, et al.Neurochemistry International|March 10, 2007
The metabolic role of isoleucine in detoxification of ammonia in cultured mouse neurons and astrocytesMaja L Johansen, Lasse K Bak, Arne Schousboe, et al.Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism|December 19, 2013
Effect of glutamine synthetase inhibition on brain and interorgan ammonia metabolism in bile duct ligated ratsAndreas W Fries, Sherry Dadsetan, Susanne Keiding, et al.Neurochemistry International|May 1, 2012
siRNA knock down of glutamate dehydrogenase in astrocytes affects glutamate metabolism leading to extensive accumulation of the neuroactive amino acids glutamate and aspartateDorte M Skytt, Anna M Klawonn, Malin H Stridh, et al.Bioorganic & Medicinal Chemistry|April 18, 2015
Structure activity relationship of selective GABA uptake inhibitorsStine B Vogensen, Lars Jørgensen, Karsten K Madsen, et al.Journal of Medicinal Chemistry|February 14, 2008
Structures of the ligand-binding core of iGluR2 in complex with the agonists (R)- and (S)-2-amino-3-(4-hydroxy-1,2,5-thiadiazol-3-yl)propionic acid explain their unusual equipotencyMads Beich-Frandsen, Darryl S Pickering, Osman Mirza, et al.American Journal of Physiology. Gastrointestinal and Liver Physiology|June 4, 2011
Branched-chain amino acids increase arterial blood ammonia in spite of enhanced intrinsic muscle ammonia metabolism in patients with cirrhosis and healthy subjectsGitte Dam, Susanne Keiding, Ole Lajord Munk, et al.Pageof 18