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Antisense & Nucleic Acid Drug Development
|
April 15, 2003
Prediction of clinical responses in a simulated phase III trial of Crohn's patients administered the antisense phosphorothioate oligonucleotide ISIS 2302: comparison of proposed dosing regimens
Rosie Z Yu, John Q Su, John S Grundy, et al.
Nucleic Acid Therapeutics
|
August 6, 2014
Mechanism of alternative complement pathway dysregulation by a phosphorothioate oligonucleotide in monkey and human serum
Scott P Henry, Mark A Jagels, Tony E Hugli, et al.
Science (New York, N.Y.)
|
March 1, 2003
More on science and politics
Gary D Bass, Paul D Blumenthal, Phil Corfman, et al.
Nucleic Acid Therapeutics
|
August 24, 2012
The Oligonucleotide Safety Working Group (OSWG)
Dave Schubert, Arthur A Levin, Doug Kornbrust, et al.
International Immunopharmacology
|
December 10, 2002
Complement activation is responsible for acute toxicities in rhesus monkeys treated with a phosphorothioate oligodeoxynucleotide
Scott P Henry, Greg Beattie, Grace Yeh, et al.
Journal of Pharmaceutical Sciences
|
May 5, 2004
Oral bioavailability and multiple dose tolerability of an antisense oligonucleotide tablet formulated with sodium caprate
Araz A Raoof, Peter Chiu, Zeibun Ramtoola, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
October 23, 2003
Pharmacokinetics of a tumor necrosis factor-alpha phosphorothioate 2'-O-(2-methoxyethyl) modified antisense oligonucleotide: comparison across species
Richard S Geary, Rosie Z Yu, Tanya Watanabe, et al.
American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation
|
April 9, 2013
Acute kidney injury during therapy with an antisense oligonucleotide directed against PCSK9
Eveline P van Poelgeest, Reinout M Swart, Michiel G H Betjes, et al.
Biochemical Pharmacology
|
December 6, 2008
Cross-species comparison of in vivo PK/PD relationships for second-generation antisense oligonucleotides targeting apolipoprotein B-100
Rosie Z Yu, Kristina M Lemonidis, Mark J Graham, et al.
British Journal of Clinical Pharmacology
|
August 12, 2015
Antisense-mediated reduction of proprotein convertase subtilisin/kexin type 9 (PCSK9): a first-in-human randomized, placebo-controlled trial
Eveline P van Poelgeest, Michael R Hodges, Matthijs Moerland, et al.
Page
of 4
Search research articles
Search
Showing results (21-30 of 40) with videos related to
Sort By:
Page
of 4
Antisense & Nucleic Acid Drug Development
|
April 15, 2003
Prediction of clinical responses in a simulated phase III trial of Crohn's patients administered the antisense phosphorothioate oligonucleotide ISIS 2302: comparison of proposed dosing regimens
Rosie Z Yu, John Q Su, John S Grundy, et al.
Nucleic Acid Therapeutics
|
August 6, 2014
Mechanism of alternative complement pathway dysregulation by a phosphorothioate oligonucleotide in monkey and human serum
Scott P Henry, Mark A Jagels, Tony E Hugli, et al.
Science (New York, N.Y.)
|
March 1, 2003
More on science and politics
Gary D Bass, Paul D Blumenthal, Phil Corfman, et al.
Nucleic Acid Therapeutics
|
August 24, 2012
The Oligonucleotide Safety Working Group (OSWG)
Dave Schubert, Arthur A Levin, Doug Kornbrust, et al.
International Immunopharmacology
|
December 10, 2002
Complement activation is responsible for acute toxicities in rhesus monkeys treated with a phosphorothioate oligodeoxynucleotide
Scott P Henry, Greg Beattie, Grace Yeh, et al.
Journal of Pharmaceutical Sciences
|
May 5, 2004
Oral bioavailability and multiple dose tolerability of an antisense oligonucleotide tablet formulated with sodium caprate
Araz A Raoof, Peter Chiu, Zeibun Ramtoola, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
October 23, 2003
Pharmacokinetics of a tumor necrosis factor-alpha phosphorothioate 2'-O-(2-methoxyethyl) modified antisense oligonucleotide: comparison across species
Richard S Geary, Rosie Z Yu, Tanya Watanabe, et al.
American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation
|
April 9, 2013
Acute kidney injury during therapy with an antisense oligonucleotide directed against PCSK9
Eveline P van Poelgeest, Reinout M Swart, Michiel G H Betjes, et al.
Biochemical Pharmacology
|
December 6, 2008
Cross-species comparison of in vivo PK/PD relationships for second-generation antisense oligonucleotides targeting apolipoprotein B-100
Rosie Z Yu, Kristina M Lemonidis, Mark J Graham, et al.
British Journal of Clinical Pharmacology
|
August 12, 2015
Antisense-mediated reduction of proprotein convertase subtilisin/kexin type 9 (PCSK9): a first-in-human randomized, placebo-controlled trial
Eveline P van Poelgeest, Michael R Hodges, Matthijs Moerland, et al.
Page
of 4