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Arthur Christopoulos

Showing results (101-110 of 331) with videos related to

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Journal of Medicinal Chemistry|October 1, 2013
Probing structural requirements of positive allosteric modulators of the M4 muscarinic receptorTracey Huynh, Celine Valant, Ian T Crosby, et al.
Biochemical Pharmacology|December 30, 2023
Ligand-directed biased agonism at human histamine H<sub>3</sub> receptor isoforms across Gα<sub>i/o</sub>- and β-arrestin2-mediated pathwaysSabrina N Rahman, Faissal Imhaouran, Rob Leurs, et al.
Endocrinology|January 3, 2012
Positive and negative allosteric modulators promote biased signaling at the calcium-sensing receptorAnna E Davey, Katie Leach, Celine Valant, et al.
Journal of Medicinal Chemistry|January 16, 2015
Proof of concept study for designed multiple ligands targeting the dopamine D2, serotonin 5-HT2A, and muscarinic M1 acetylcholine receptorsMonika Szabo, Herman D Lim, Carmen Klein Herenbrink, et al.
Neuropharmacology|July 10, 2016
Biased allosteric agonism and modulation of metabotropic glutamate receptor 5: Implications for optimizing preclinical neuroscience drug discoveryKathy Sengmany, Junaid Singh, Gregory D Stewart, et al.
Molecular Pharmacology|May 28, 2015
Biased Agonism of Endogenous Opioid Peptides at the μ-Opioid ReceptorGeorgina L Thompson, J Robert Lane, Thomas Coudrat, et al.
Nature Reviews. Drug Discovery|June 7, 2014
Muscarinic acetylcholine receptors: novel opportunities for drug developmentAndrew C Kruse, Brian K Kobilka, Dinesh Gautam, et al.
Molecular Pharmacology|July 3, 2008
Identification of N-terminal receptor activity-modifying protein residues important for calcitonin gene-related peptide, adrenomedullin, and amylin receptor functionTao Qi, George Christopoulos, Richard J Bailey, et al.
Biochemical Pharmacology|May 12, 2020
Probe dependence and biased potentiation of metabotropic glutamate receptor 5 is mediated by differential ligand interactions in the common allosteric binding siteShane D Hellyer, Kathy Sengmany, Andrew N Keller, et al.
Journal of Medicinal Chemistry|May 31, 2013
Synthesis and pharmacological profiling of analogues of benzyl quinolone carboxylic acid (BQCA) as allosteric modulators of the M1 muscarinic receptorShailesh N Mistry, Celine Valant, Patrick M Sexton, et al.
Pageof 34

Showing results (101-110 of 331) with videos related to

Sort By:
Pageof 34
Journal of Medicinal Chemistry|October 1, 2013
Probing structural requirements of positive allosteric modulators of the M4 muscarinic receptorTracey Huynh, Celine Valant, Ian T Crosby, et al.
Biochemical Pharmacology|December 30, 2023
Ligand-directed biased agonism at human histamine H<sub>3</sub> receptor isoforms across Gα<sub>i/o</sub>- and β-arrestin2-mediated pathwaysSabrina N Rahman, Faissal Imhaouran, Rob Leurs, et al.
Endocrinology|January 3, 2012
Positive and negative allosteric modulators promote biased signaling at the calcium-sensing receptorAnna E Davey, Katie Leach, Celine Valant, et al.
Journal of Medicinal Chemistry|January 16, 2015
Proof of concept study for designed multiple ligands targeting the dopamine D2, serotonin 5-HT2A, and muscarinic M1 acetylcholine receptorsMonika Szabo, Herman D Lim, Carmen Klein Herenbrink, et al.
Neuropharmacology|July 10, 2016
Biased allosteric agonism and modulation of metabotropic glutamate receptor 5: Implications for optimizing preclinical neuroscience drug discoveryKathy Sengmany, Junaid Singh, Gregory D Stewart, et al.
Molecular Pharmacology|May 28, 2015
Biased Agonism of Endogenous Opioid Peptides at the μ-Opioid ReceptorGeorgina L Thompson, J Robert Lane, Thomas Coudrat, et al.
Nature Reviews. Drug Discovery|June 7, 2014
Muscarinic acetylcholine receptors: novel opportunities for drug developmentAndrew C Kruse, Brian K Kobilka, Dinesh Gautam, et al.
Molecular Pharmacology|July 3, 2008
Identification of N-terminal receptor activity-modifying protein residues important for calcitonin gene-related peptide, adrenomedullin, and amylin receptor functionTao Qi, George Christopoulos, Richard J Bailey, et al.
Biochemical Pharmacology|May 12, 2020
Probe dependence and biased potentiation of metabotropic glutamate receptor 5 is mediated by differential ligand interactions in the common allosteric binding siteShane D Hellyer, Kathy Sengmany, Andrew N Keller, et al.
Journal of Medicinal Chemistry|May 31, 2013
Synthesis and pharmacological profiling of analogues of benzyl quinolone carboxylic acid (BQCA) as allosteric modulators of the M1 muscarinic receptorShailesh N Mistry, Celine Valant, Patrick M Sexton, et al.
Pageof 34