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Molecular Pharmacology
|
July 17, 2008
New insights into the function of M4 muscarinic acetylcholine receptors gained using a novel allosteric modulator and a DREADD (designer receptor exclusively activated by a designer drug)
Vindhya Nawaratne, Katie Leach, Nur Suratman, et al.
Biochemical Pharmacology
|
May 20, 2018
Probing the binding site of novel selective positive allosteric modulators at the M<sub>1</sub> muscarinic acetylcholine receptor
Elham Khajehali, Celine Valant, Manuela Jörg, et al.
Biochemical Pharmacology
|
August 30, 2016
Key interactions by conserved polar amino acids located at the transmembrane helical boundaries in Class B GPCRs modulate activation, effector specificity and biased signalling in the glucagon-like peptide-1 receptor
Denise Wootten, Christopher A Reynolds, Kevin J Smith, et al.
Journal of Medicinal Chemistry
|
October 23, 2025
Structure-Activity Relationships of Highly Potent and Selective A<sub>2B</sub> Adenosine Receptor Agonists
Christopher J Smedley, Jon Kyle Awalt, Anh T N Nguyen, et al.
Journal of Medicinal Chemistry
|
December 2, 2015
4-Phenylpyridin-2-one Derivatives: A Novel Class of Positive Allosteric Modulator of the M1 Muscarinic Acetylcholine Receptor
Shailesh N Mistry, Manuela Jörg, Herman Lim, et al.
Molecular Pharmacology
|
June 16, 2010
Allosteric ligands of the glucagon-like peptide 1 receptor (GLP-1R) differentially modulate endogenous and exogenous peptide responses in a pathway-selective manner: implications for drug screening
Cassandra Koole, Denise Wootten, John Simms, et al.
Cell
|
February 25, 2017
Structure of the Adenosine A<sub>1</sub> Receptor Reveals the Basis for Subtype Selectivity
Alisa Glukhova, David M Thal, Anh T Nguyen, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
March 13, 2014
Separation of on-target efficacy from adverse effects through rational design of a bitopic adenosine receptor agonist
Celine Valant, Lauren T May, Luigi Aurelio, et al.
British Journal of Pharmacology
|
April 19, 2023
The role of the adenosine system in epilepsy and its comorbidities
Jo-Anne Baltos, Pablo M Casillas-Espinosa, Ben Rollo, et al.
Journal of Medicinal Chemistry
|
September 6, 2008
2-aminothienopyridazines as novel adenosine A1 receptor allosteric modulators and antagonists
Gemma N Ferguson, Celine Valant, James Horne, et al.
Page
of 34
Search research articles
Search
Showing results (201-210 of 331) with videos related to
Sort By:
Page
of 34
Molecular Pharmacology
|
July 17, 2008
New insights into the function of M4 muscarinic acetylcholine receptors gained using a novel allosteric modulator and a DREADD (designer receptor exclusively activated by a designer drug)
Vindhya Nawaratne, Katie Leach, Nur Suratman, et al.
Biochemical Pharmacology
|
May 20, 2018
Probing the binding site of novel selective positive allosteric modulators at the M<sub>1</sub> muscarinic acetylcholine receptor
Elham Khajehali, Celine Valant, Manuela Jörg, et al.
Biochemical Pharmacology
|
August 30, 2016
Key interactions by conserved polar amino acids located at the transmembrane helical boundaries in Class B GPCRs modulate activation, effector specificity and biased signalling in the glucagon-like peptide-1 receptor
Denise Wootten, Christopher A Reynolds, Kevin J Smith, et al.
Journal of Medicinal Chemistry
|
October 23, 2025
Structure-Activity Relationships of Highly Potent and Selective A<sub>2B</sub> Adenosine Receptor Agonists
Christopher J Smedley, Jon Kyle Awalt, Anh T N Nguyen, et al.
Journal of Medicinal Chemistry
|
December 2, 2015
4-Phenylpyridin-2-one Derivatives: A Novel Class of Positive Allosteric Modulator of the M1 Muscarinic Acetylcholine Receptor
Shailesh N Mistry, Manuela Jörg, Herman Lim, et al.
Molecular Pharmacology
|
June 16, 2010
Allosteric ligands of the glucagon-like peptide 1 receptor (GLP-1R) differentially modulate endogenous and exogenous peptide responses in a pathway-selective manner: implications for drug screening
Cassandra Koole, Denise Wootten, John Simms, et al.
Cell
|
February 25, 2017
Structure of the Adenosine A<sub>1</sub> Receptor Reveals the Basis for Subtype Selectivity
Alisa Glukhova, David M Thal, Anh T Nguyen, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
March 13, 2014
Separation of on-target efficacy from adverse effects through rational design of a bitopic adenosine receptor agonist
Celine Valant, Lauren T May, Luigi Aurelio, et al.
British Journal of Pharmacology
|
April 19, 2023
The role of the adenosine system in epilepsy and its comorbidities
Jo-Anne Baltos, Pablo M Casillas-Espinosa, Ben Rollo, et al.
Journal of Medicinal Chemistry
|
September 6, 2008
2-aminothienopyridazines as novel adenosine A1 receptor allosteric modulators and antagonists
Gemma N Ferguson, Celine Valant, James Horne, et al.
Page
of 34