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Arthur Christopoulos

Showing results (51-60 of 331) with videos related to

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Molecular Pharmacology|September 15, 2018
Utility of an "Allosteric Site-Impaired" M<sub>2</sub> Muscarinic Acetylcholine Receptor as a Novel Construct for Validating Mechanisms of Action of Synthetic and Putative Endogenous Allosteric ModulatorsEe Von Moo, Patrick M Sexton, Arthur Christopoulos, et al.
Molecular Pharmacology|September 9, 2006
Determinants of 1-piperidinecarboxamide, N-[2-[[5-amino-l-[[4-(4-pyridinyl)-l-piperazinyl]carbonyl]pentyl]amino]-1-[(3,5-dibromo-4-hydroxyphenyl)methyl]-2-oxoethyl]-4-(1,4-dihydro-2-oxo-3(2H)-quinazolinyl) (BIBN4096BS) affinity for calcitonin gene-related peptide and amylin receptors--the role of receptor activity modifying protein 1Debbie L Hay, George Christopoulos, Arthur Christopoulos, et al.
The Journal of Pharmacology and Experimental Therapeutics|August 31, 2004
Regulation of M2 muscarinic acetylcholine receptor expression and signaling by prolonged exposure to allosteric modulatorsLauren T May, Yvonne Lin, Patrick M Sexton, et al.
Annual Review of Pharmacology and Toxicology|September 14, 2011
The best of both worlds? Bitopic orthosteric/allosteric ligands of g protein-coupled receptorsCeline Valant, J Robert Lane, Patrick M Sexton, et al.
Pharmacology & Therapeutics|June 17, 2008
RNA editing of the serotonin 5HT2C receptor and its effects on cell signalling, pharmacology and brain functionTim D Werry, Richard Loiacono, Patrick M Sexton, et al.
Plos Computational Biology|November 14, 2017
Improving virtual screening of G protein-coupled receptors via ligand-directed modelingThomas Coudrat, John Simms, Arthur Christopoulos, et al.
British Journal of Pharmacology|July 2, 2011
Consequences of splice variation on Secretin family G protein-coupled receptor functionSebastian G B Furness, Denise Wootten, Arthur Christopoulos, et al.
The Journal of Pharmacology and Experimental Therapeutics|March 7, 2008
The impact of orthosteric radioligand depletion on the quantification of allosteric modulator interactionsVimesh A Avlani, David J McLoughlin, Patrick M Sexton, et al.
The Journal of Biological Chemistry|September 12, 2012
Stimulus bias provides evidence for conformational constraints in the structure of a G protein-coupled receptorKaren J Gregory, Patrick M Sexton, Andrew B Tobin, et al.
Molecular Pharmacology|December 25, 2013
Quantification of ligand bias for clinically relevant β2-adrenergic receptor ligands: implications for drug taxonomyEmma T van der Westhuizen, Billy Breton, Arthur Christopoulos, et al.
Pageof 34

Showing results (51-60 of 331) with videos related to

Sort By:
Pageof 34
Molecular Pharmacology|September 15, 2018
Utility of an "Allosteric Site-Impaired" M<sub>2</sub> Muscarinic Acetylcholine Receptor as a Novel Construct for Validating Mechanisms of Action of Synthetic and Putative Endogenous Allosteric ModulatorsEe Von Moo, Patrick M Sexton, Arthur Christopoulos, et al.
Molecular Pharmacology|September 9, 2006
Determinants of 1-piperidinecarboxamide, N-[2-[[5-amino-l-[[4-(4-pyridinyl)-l-piperazinyl]carbonyl]pentyl]amino]-1-[(3,5-dibromo-4-hydroxyphenyl)methyl]-2-oxoethyl]-4-(1,4-dihydro-2-oxo-3(2H)-quinazolinyl) (BIBN4096BS) affinity for calcitonin gene-related peptide and amylin receptors--the role of receptor activity modifying protein 1Debbie L Hay, George Christopoulos, Arthur Christopoulos, et al.
The Journal of Pharmacology and Experimental Therapeutics|August 31, 2004
Regulation of M2 muscarinic acetylcholine receptor expression and signaling by prolonged exposure to allosteric modulatorsLauren T May, Yvonne Lin, Patrick M Sexton, et al.
Annual Review of Pharmacology and Toxicology|September 14, 2011
The best of both worlds? Bitopic orthosteric/allosteric ligands of g protein-coupled receptorsCeline Valant, J Robert Lane, Patrick M Sexton, et al.
Pharmacology & Therapeutics|June 17, 2008
RNA editing of the serotonin 5HT2C receptor and its effects on cell signalling, pharmacology and brain functionTim D Werry, Richard Loiacono, Patrick M Sexton, et al.
Plos Computational Biology|November 14, 2017
Improving virtual screening of G protein-coupled receptors via ligand-directed modelingThomas Coudrat, John Simms, Arthur Christopoulos, et al.
British Journal of Pharmacology|July 2, 2011
Consequences of splice variation on Secretin family G protein-coupled receptor functionSebastian G B Furness, Denise Wootten, Arthur Christopoulos, et al.
The Journal of Pharmacology and Experimental Therapeutics|March 7, 2008
The impact of orthosteric radioligand depletion on the quantification of allosteric modulator interactionsVimesh A Avlani, David J McLoughlin, Patrick M Sexton, et al.
The Journal of Biological Chemistry|September 12, 2012
Stimulus bias provides evidence for conformational constraints in the structure of a G protein-coupled receptorKaren J Gregory, Patrick M Sexton, Andrew B Tobin, et al.
Molecular Pharmacology|December 25, 2013
Quantification of ligand bias for clinically relevant β2-adrenergic receptor ligands: implications for drug taxonomyEmma T van der Westhuizen, Billy Breton, Arthur Christopoulos, et al.
Pageof 34