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Arvind Mathur

Showing results (131-140 of 148) with videos related to

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BMC Geriatrics|December 3, 2025
Development and validation of a deprescribing tool relevant to older persons in India using modified Delphi consensus techniqueRatinder Jhaj, Atiya R Faruqui, Santanu Kumar Tripathi, et al.
ACS Medicinal Chemistry Letters|July 16, 2021
Conformational-Analysis-Guided Discovery of 2,3-Disubstituted Pyridine IDO1 InhibitorsEmily C Cherney, Liping Zhang, Weiwei Guo, et al.
Journal of Medicinal Chemistry|January 24, 2017
Discovery of Pyrrolidine-Containing GPR40 Agonists: Stereochemistry Effects a Change in Binding ModeElizabeth A Jurica, Ximao Wu, Kristin N Williams, et al.
Journal of Medicinal Chemistry|February 21, 2019
Identification and Preclinical Pharmacology of ((1 R,3 S)-1-Amino-3-(( S)-6-(2-methoxyphenethyl)-5,6,7,8-tetrahydronaphthalen-2-yl)cyclopentyl)methanol (BMS-986166): A Differentiated Sphingosine-1-phosphate Receptor 1 (S1P<sub>1</sub>) Modulator Advanced into Clinical TrialsJohn L Gilmore, Hai-Yun Xiao, T G Murali Dhar, et al.
Journal of Medicinal Chemistry|January 10, 2018
Discovery of Potent and Orally Bioavailable Dihydropyrazole GPR40 AgonistsJun Shi, Zhengxiang Gu, Elizabeth Anne Jurica, et al.
Bioorganic & Medicinal Chemistry|April 8, 2023
Optimization of physicochemical properties of pyrrolidine GPR40 AgoPAMs results in a differentiated profile with improved pharmacokinetics and reduced off-target activitiesElizabeth A Jurica, Ximao Wu, Kristin N Williams, et al.
Journal of Medicinal Chemistry|October 12, 2016
Identification of Tricyclic Agonists of Sphingosine-1-phosphate Receptor 1 (S1P<sub>1</sub>) Employing Ligand-Based Drug DesignHai-Yun Xiao, Scott H Watterson, Charles M Langevine, et al.
Journal of Medicinal Chemistry|September 20, 2021
Discovery and Preclinical Pharmacology of an Oral Bromodomain and Extra-Terminal (BET) Inhibitor Using Scaffold-Hopping and Structure-Guided Drug DesignAshvinikumar V Gavai, Derek Norris, George Delucca, et al.
The Journal of Pharmacology and Experimental Therapeutics|September 29, 2017
Preclinical Characterization of (<i>R</i>)-3-((3<i>S</i>,4<i>S</i>)-3-fluoro-4-(4-hydroxyphenyl)piperidin-1-yl)-1-(4-methylbenzyl)pyrrolidin-2-one (BMS-986169), a Novel, Intravenous, Glutamate <i>N</i>-Methyl-d-Aspartate 2B Receptor Negative Allosteric Modulator with Potential in Major Depressive DisorderLinda J Bristow, Jyoti Gulia, Michael R Weed, et al.
Journal of Medicinal Chemistry|March 21, 2019
Discovery of Branebrutinib (BMS-986195): A Strategy for Identifying a Highly Potent and Selective Covalent Inhibitor Providing Rapid in Vivo Inactivation of Bruton's Tyrosine Kinase (BTK)Scott H Watterson, Qingjie Liu, Myra Beaudoin Bertrand, et al.
Pageof 15

Showing results (131-140 of 148) with videos related to

Sort By:
Pageof 15
BMC Geriatrics|December 3, 2025
Development and validation of a deprescribing tool relevant to older persons in India using modified Delphi consensus techniqueRatinder Jhaj, Atiya R Faruqui, Santanu Kumar Tripathi, et al.
ACS Medicinal Chemistry Letters|July 16, 2021
Conformational-Analysis-Guided Discovery of 2,3-Disubstituted Pyridine IDO1 InhibitorsEmily C Cherney, Liping Zhang, Weiwei Guo, et al.
Journal of Medicinal Chemistry|January 24, 2017
Discovery of Pyrrolidine-Containing GPR40 Agonists: Stereochemistry Effects a Change in Binding ModeElizabeth A Jurica, Ximao Wu, Kristin N Williams, et al.
Journal of Medicinal Chemistry|February 21, 2019
Identification and Preclinical Pharmacology of ((1 R,3 S)-1-Amino-3-(( S)-6-(2-methoxyphenethyl)-5,6,7,8-tetrahydronaphthalen-2-yl)cyclopentyl)methanol (BMS-986166): A Differentiated Sphingosine-1-phosphate Receptor 1 (S1P<sub>1</sub>) Modulator Advanced into Clinical TrialsJohn L Gilmore, Hai-Yun Xiao, T G Murali Dhar, et al.
Journal of Medicinal Chemistry|January 10, 2018
Discovery of Potent and Orally Bioavailable Dihydropyrazole GPR40 AgonistsJun Shi, Zhengxiang Gu, Elizabeth Anne Jurica, et al.
Bioorganic & Medicinal Chemistry|April 8, 2023
Optimization of physicochemical properties of pyrrolidine GPR40 AgoPAMs results in a differentiated profile with improved pharmacokinetics and reduced off-target activitiesElizabeth A Jurica, Ximao Wu, Kristin N Williams, et al.
Journal of Medicinal Chemistry|October 12, 2016
Identification of Tricyclic Agonists of Sphingosine-1-phosphate Receptor 1 (S1P<sub>1</sub>) Employing Ligand-Based Drug DesignHai-Yun Xiao, Scott H Watterson, Charles M Langevine, et al.
Journal of Medicinal Chemistry|September 20, 2021
Discovery and Preclinical Pharmacology of an Oral Bromodomain and Extra-Terminal (BET) Inhibitor Using Scaffold-Hopping and Structure-Guided Drug DesignAshvinikumar V Gavai, Derek Norris, George Delucca, et al.
The Journal of Pharmacology and Experimental Therapeutics|September 29, 2017
Preclinical Characterization of (<i>R</i>)-3-((3<i>S</i>,4<i>S</i>)-3-fluoro-4-(4-hydroxyphenyl)piperidin-1-yl)-1-(4-methylbenzyl)pyrrolidin-2-one (BMS-986169), a Novel, Intravenous, Glutamate <i>N</i>-Methyl-d-Aspartate 2B Receptor Negative Allosteric Modulator with Potential in Major Depressive DisorderLinda J Bristow, Jyoti Gulia, Michael R Weed, et al.
Journal of Medicinal Chemistry|March 21, 2019
Discovery of Branebrutinib (BMS-986195): A Strategy for Identifying a Highly Potent and Selective Covalent Inhibitor Providing Rapid in Vivo Inactivation of Bruton's Tyrosine Kinase (BTK)Scott H Watterson, Qingjie Liu, Myra Beaudoin Bertrand, et al.
Pageof 15