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The Journal of Organic Chemistry
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April 23, 2024
Challenges with the Synthesis of a Macrocyclic Thioether Peptide: From Milligram to Multigram Using Solid Phase Peptide Synthesis (SPPS)
James Kempson, Rulin Zhao, Joseph Pawluczyk, et al.
Journal of Combinatorial Chemistry
|
December 18, 2008
Design and synthesis of a G-protein-coupled receptor antagonist library of aryloxyalkanolamines using a polymer-supported acyclic acetal linker
Jacques Y Roberge, Lalgudi S Harikrishnan, Muthoni G Kamau, et al.
Bioorganic & Medicinal Chemistry Letters
|
February 3, 2007
New C-5 substituted pyrrolotriazine dual inhibitors of EGFR and HER2 protein tyrosine kinases
Harold Mastalerz, Ming Chang, Ping Chen, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 3, 2020
Discovery of (3S,4S)-3-methyl-3-(4-fluorophenyl)-4-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxyprop-2-yl)phenyl)pyrrolidines as novel RORγt inverse agonists
Bin Jiang, James J-W Duan, Sylwia Stachura, et al.
Journal of Medicinal Chemistry
|
May 28, 2025
The Discovery of C7-Substituted Norbornyl Bisamides as RXFP1 Small Molecule Agonists
Shun Su, Michael C Myers, Donna M Bilder, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 9, 2008
Discovery and preclinical studies of 5-isopropyl-6-(5-methyl-1,3,4-oxadiazol-2-yl)-N-(2-methyl-1H-pyrrolo[2,3-b]pyridin-5-yl)pyrrolo[2,1-f][1,2,4]triazin-4-amine (BMS-645737), an in vivo active potent VEGFR-2 inhibitor
Réjean Ruel, Carl Thibeault, Alexandre L'Heureux, et al.
Bioorganic & Medicinal Chemistry
|
February 23, 2024
Identification of benzothiazole derived monosaccharides as potent, selective, and orally bioavailable inhibitors of human and mouse galectin-3; a rare example of using a S···O binding interaction for drug design
Chunjian Liu, Wei Wang, Jianxin Feng, et al.
Journal of Medicinal Chemistry
|
November 6, 2020
Design, Synthesis, and Structure-Activity Relationships of Novel Tetrahydroisoquinolino Benzodiazepine Dimer Antitumor Agents and Their Application in Antibody-Drug Conjugates
Naidu S Chowdari, Yong Zhang, Ivar McDonald, et al.
ACS Medicinal Chemistry Letters
|
September 18, 2020
Aryl Ether-Derived Sphingosine-1-Phosphate Receptor (S1P<sub>1</sub>) Modulators: Optimization of the PK, PD, and Safety Profiles
Zili Xiao, Michael G Yang, T G Murali Dhar, et al.
Journal of Medicinal Chemistry
|
June 26, 2007
Acridone-based inhibitors of inosine 5'-monophosphate dehydrogenase: discovery and SAR leading to the identification of N-(2-(6-(4-ethylpiperazin-1-yl)pyridin-3-yl)propan-2-yl)-2- fluoro-9-oxo-9,10-dihydroacridine-3-carboxamide (BMS-566419)
Scott H Watterson, Ping Chen, Yufen Zhao, et al.
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of 15
Search research articles
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Showing results (71-80 of 148) with videos related to
Sort By:
Page
of 15
The Journal of Organic Chemistry
|
April 23, 2024
Challenges with the Synthesis of a Macrocyclic Thioether Peptide: From Milligram to Multigram Using Solid Phase Peptide Synthesis (SPPS)
James Kempson, Rulin Zhao, Joseph Pawluczyk, et al.
Journal of Combinatorial Chemistry
|
December 18, 2008
Design and synthesis of a G-protein-coupled receptor antagonist library of aryloxyalkanolamines using a polymer-supported acyclic acetal linker
Jacques Y Roberge, Lalgudi S Harikrishnan, Muthoni G Kamau, et al.
Bioorganic & Medicinal Chemistry Letters
|
February 3, 2007
New C-5 substituted pyrrolotriazine dual inhibitors of EGFR and HER2 protein tyrosine kinases
Harold Mastalerz, Ming Chang, Ping Chen, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 3, 2020
Discovery of (3S,4S)-3-methyl-3-(4-fluorophenyl)-4-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxyprop-2-yl)phenyl)pyrrolidines as novel RORγt inverse agonists
Bin Jiang, James J-W Duan, Sylwia Stachura, et al.
Journal of Medicinal Chemistry
|
May 28, 2025
The Discovery of C7-Substituted Norbornyl Bisamides as RXFP1 Small Molecule Agonists
Shun Su, Michael C Myers, Donna M Bilder, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 9, 2008
Discovery and preclinical studies of 5-isopropyl-6-(5-methyl-1,3,4-oxadiazol-2-yl)-N-(2-methyl-1H-pyrrolo[2,3-b]pyridin-5-yl)pyrrolo[2,1-f][1,2,4]triazin-4-amine (BMS-645737), an in vivo active potent VEGFR-2 inhibitor
Réjean Ruel, Carl Thibeault, Alexandre L'Heureux, et al.
Bioorganic & Medicinal Chemistry
|
February 23, 2024
Identification of benzothiazole derived monosaccharides as potent, selective, and orally bioavailable inhibitors of human and mouse galectin-3; a rare example of using a S···O binding interaction for drug design
Chunjian Liu, Wei Wang, Jianxin Feng, et al.
Journal of Medicinal Chemistry
|
November 6, 2020
Design, Synthesis, and Structure-Activity Relationships of Novel Tetrahydroisoquinolino Benzodiazepine Dimer Antitumor Agents and Their Application in Antibody-Drug Conjugates
Naidu S Chowdari, Yong Zhang, Ivar McDonald, et al.
ACS Medicinal Chemistry Letters
|
September 18, 2020
Aryl Ether-Derived Sphingosine-1-Phosphate Receptor (S1P<sub>1</sub>) Modulators: Optimization of the PK, PD, and Safety Profiles
Zili Xiao, Michael G Yang, T G Murali Dhar, et al.
Journal of Medicinal Chemistry
|
June 26, 2007
Acridone-based inhibitors of inosine 5'-monophosphate dehydrogenase: discovery and SAR leading to the identification of N-(2-(6-(4-ethylpiperazin-1-yl)pyridin-3-yl)propan-2-yl)-2- fluoro-9-oxo-9,10-dihydroacridine-3-carboxamide (BMS-566419)
Scott H Watterson, Ping Chen, Yufen Zhao, et al.
Page
of 15