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Arvind Mathur

Showing results (81-90 of 148) with videos related to

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Journal of Medicinal Chemistry|March 30, 2026
From Flat to 3D: Replacing Phenyl Rings with Saturated Bridged Bicyclic Mimetics to Mitigate Bioactivation and Optimize ADME Properties and Oral Bioavailability in Reverse Amide OrientationMurugaiah A M Subbaiah, Shruti Surendran, Gaurav Saini, et al.
The Journal of Organic Chemistry|June 14, 2021
A Stereocontrolled Synthesis of a Phosphorothioate Cyclic Dinucleotide-Based STING AgonistJames Kempson, Huiping Zhang, Xiaoping Hou, et al.
Bioorganic & Medicinal Chemistry Letters|June 22, 2017
Discovery of BMS-961955, an allosteric inhibitor of the hepatitis C virus NS5B polymeraseBarbara Zhizhen Zheng, Stanley V D'Andrea, Umesh Hanumegowda, et al.
Journal of Medicinal Chemistry|January 25, 2021
Bicyclic Ligand-Biased Agonists of S1P<sub>1</sub>: Exploring Side Chain Modifications to Modulate the PK, PD, and Safety ProfilesJohn L Gilmore, Hai-Yun Xiao, T G Murali Dhar, et al.
Bioorganic & Medicinal Chemistry Letters|July 2, 2019
Identification of potent, selective and orally bioavailable phenyl ((R)-3-phenylpyrrolidin-3-yl)sulfone analogues as RORγt inverse agonistsZhonghui Lu, James J-W Duan, Haiyun Xiao, et al.
ACS Medicinal Chemistry Letters|February 20, 2018
Potent Inhibitors of Hepatitis C Virus NS3 Protease: Employment of a Difluoromethyl Group as a Hydrogen-Bond DonorBarbara Zheng, Stanley V D'Andrea, Li-Qiang Sun, et al.
Journal of Medicinal Chemistry|August 15, 2022
Identification of Monosaccharide Derivatives as Potent, Selective, and Orally Bioavailable Inhibitors of Human and Mouse Galectin-3Chunjian Liu, Prasada Rao Jalagam, Jianxin Feng, et al.
Bioorganic & Medicinal Chemistry Letters|June 9, 2023
Discovery of novel pyridinones as MGAT2 inhibitors for the treatment of metabolic disordersFang Moore, Wei Wang, Guohua Zhao, et al.
ACS Medicinal Chemistry Letters|March 21, 2019
Structure-based Discovery of Phenyl (3-Phenylpyrrolidin-3-yl)sulfones as Selective, Orally Active RORγt Inverse AgonistsJames J-W Duan, Zhonghui Lu, Bin Jiang, et al.
ACS Medicinal Chemistry Letters|June 18, 2021
Discovery of BMS-753426: A Potent Orally Bioavailable Antagonist of CC Chemokine Receptor 2Michael G Yang, Zili Xiao, Rulin Zhao, et al.
Pageof 15

Showing results (81-90 of 148) with videos related to

Sort By:
Pageof 15
Journal of Medicinal Chemistry|March 30, 2026
From Flat to 3D: Replacing Phenyl Rings with Saturated Bridged Bicyclic Mimetics to Mitigate Bioactivation and Optimize ADME Properties and Oral Bioavailability in Reverse Amide OrientationMurugaiah A M Subbaiah, Shruti Surendran, Gaurav Saini, et al.
The Journal of Organic Chemistry|June 14, 2021
A Stereocontrolled Synthesis of a Phosphorothioate Cyclic Dinucleotide-Based STING AgonistJames Kempson, Huiping Zhang, Xiaoping Hou, et al.
Bioorganic & Medicinal Chemistry Letters|June 22, 2017
Discovery of BMS-961955, an allosteric inhibitor of the hepatitis C virus NS5B polymeraseBarbara Zhizhen Zheng, Stanley V D'Andrea, Umesh Hanumegowda, et al.
Journal of Medicinal Chemistry|January 25, 2021
Bicyclic Ligand-Biased Agonists of S1P<sub>1</sub>: Exploring Side Chain Modifications to Modulate the PK, PD, and Safety ProfilesJohn L Gilmore, Hai-Yun Xiao, T G Murali Dhar, et al.
Bioorganic & Medicinal Chemistry Letters|July 2, 2019
Identification of potent, selective and orally bioavailable phenyl ((R)-3-phenylpyrrolidin-3-yl)sulfone analogues as RORγt inverse agonistsZhonghui Lu, James J-W Duan, Haiyun Xiao, et al.
ACS Medicinal Chemistry Letters|February 20, 2018
Potent Inhibitors of Hepatitis C Virus NS3 Protease: Employment of a Difluoromethyl Group as a Hydrogen-Bond DonorBarbara Zheng, Stanley V D'Andrea, Li-Qiang Sun, et al.
Journal of Medicinal Chemistry|August 15, 2022
Identification of Monosaccharide Derivatives as Potent, Selective, and Orally Bioavailable Inhibitors of Human and Mouse Galectin-3Chunjian Liu, Prasada Rao Jalagam, Jianxin Feng, et al.
Bioorganic & Medicinal Chemistry Letters|June 9, 2023
Discovery of novel pyridinones as MGAT2 inhibitors for the treatment of metabolic disordersFang Moore, Wei Wang, Guohua Zhao, et al.
ACS Medicinal Chemistry Letters|March 21, 2019
Structure-based Discovery of Phenyl (3-Phenylpyrrolidin-3-yl)sulfones as Selective, Orally Active RORγt Inverse AgonistsJames J-W Duan, Zhonghui Lu, Bin Jiang, et al.
ACS Medicinal Chemistry Letters|June 18, 2021
Discovery of BMS-753426: A Potent Orally Bioavailable Antagonist of CC Chemokine Receptor 2Michael G Yang, Zili Xiao, Rulin Zhao, et al.
Pageof 15