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Biorxiv : the Preprint Server for Biology|September 26, 2025
Dual EZH1/2 inhibition enhances DNMT inhibitor efficacy in colon cancer through targeting H3K27me1Alison A Chomiak, Ashley K Wiseman, Joel Hrit, et al.
ACS Omega|August 8, 2026
A Derivatization-Free Parallel Reaction Monitoring-Based Proteomics Workflow for Quantitative, Site-Specific Analysis of Histone Post-Translational ModificationsHyoungjoo Lee, Ashley K Wiseman, Bailey M Tibben, et al.
Communications Biology|June 2, 2022
Chromosome-specific retention of cancer-associated DNA hypermethylation following pharmacological inhibition of DNMT1Ashley K Wiseman, Rochelle L Tiedemann, Huihui Fan, et al.
Science Advances|March 27, 2024
Select EZH2 inhibitors enhance viral mimicry effects of DNMT inhibition through a mechanism involving NFAT:AP-1 signalingAlison A Chomiak, Rochelle L Tiedemann, Yanqing Liu, et al.
Molecular Cell|December 4, 2024
DNA hypomethylation promotes UHRF1-and SUV39H1/H2-dependent crosstalk between H3K18ub and H3K9me3 to reinforce heterochromatin statesYanqing Liu, Joel A Hrit, Alison A Chomiak, et al.
Biorxiv : the Preprint Server for Biology|February 26, 2024
UHRF1 ubiquitin ligase activity supports the maintenance of low-density CpG methylationRochelle L Tiedemann, Joel Hrit, Qian Du, et al.
Nucleic Acids Research|November 28, 2024
UHRF1 ubiquitin ligase activity supports the maintenance of low-density CpG methylationRochelle L Tiedemann, Joel Hrit, Qian Du, et al.
Cell Genomics|July 25, 2022
DNA methylation dynamics and dysregulation delineated by high-throughput profiling in the mouseWanding Zhou, Toshinori Hinoue, Bret Barnes, et al.
Nature Cancer|November 18, 2021
Discovery of a first-in-class reversible DNMT1-selective inhibitor with improved tolerability and efficacy in acute myeloid leukemiaMelissa B Pappalardi, Kathryn Keenan, Mark Cockerill, et al.
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