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Scientific Reports
|
December 2, 2015
Discovery and characterization of novel inhibitors of the sodium-coupled citrate transporter (NaCT or SLC13A5)
Kim Huard, Janice Brown, Jessica C Jones, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 24, 2012
The design and synthesis of indazole and pyrazolopyridine based glucokinase activators for the treatment of type 2 diabetes mellitus
Jeffrey A Pfefferkorn, Meihua Tu, Kevin J Filipski, et al.
Medchemcomm
|
August 16, 2018
Small structural changes of the imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) inhibitors produce an improved safety profile
K Futatsugi, K Huard, D W Kung, et al.
Nature Communications
|
March 2, 2025
Screening the human druggable genome identifies ABHD17B as an anti-fibrotic target in hepatic stellate cells
Wenyang Li, Robert P Sparks, Cheng Sun, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 17, 2012
Identification of novel series of pyrazole and indole-urea based DFG-out PYK2 inhibitors
Samit K Bhattacharya, Gary E Aspnes, Scott W Bagley, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 28, 2008
Trifluoromethylpyrimidine-based inhibitors of proline-rich tyrosine kinase 2 (PYK2): structure-activity relationships and strategies for the elimination of reactive metabolite formation
Daniel P Walker, F Christopher Bi, Amit S Kalgutkar, et al.
Journal of Medicinal Chemistry
|
September 9, 2015
Discovery and Optimization of Imidazopyridine-Based Inhibitors of Diacylglycerol Acyltransferase 2 (DGAT2)
Kentaro Futatsugi, Daniel W Kung, Suvi T M Orr, et al.
Journal of Medicinal Chemistry
|
February 22, 2018
Optimization of Metabolic and Renal Clearance in a Series of Indole Acid Direct Activators of 5'-Adenosine Monophosphate-Activated Protein Kinase (AMPK)
David J Edmonds, Daniel W Kung, Amit S Kalgutkar, et al.
Journal of Medicinal Chemistry
|
December 27, 2011
Discovery of (S)-6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid as a hepatoselective glucokinase activator clinical candidate for treating type 2 diabetes mellitus
Jeffrey A Pfefferkorn, Angel Guzman-Perez, John Litchfield, et al.
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Search research articles
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Showing results (81-90 of 89) with videos related to
Sort By:
Page
of 9
You have reached the last page of results.
This site can display upto 89 results.
Scientific Reports
|
December 2, 2015
Discovery and characterization of novel inhibitors of the sodium-coupled citrate transporter (NaCT or SLC13A5)
Kim Huard, Janice Brown, Jessica C Jones, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 24, 2012
The design and synthesis of indazole and pyrazolopyridine based glucokinase activators for the treatment of type 2 diabetes mellitus
Jeffrey A Pfefferkorn, Meihua Tu, Kevin J Filipski, et al.
Medchemcomm
|
August 16, 2018
Small structural changes of the imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) inhibitors produce an improved safety profile
K Futatsugi, K Huard, D W Kung, et al.
Nature Communications
|
March 2, 2025
Screening the human druggable genome identifies ABHD17B as an anti-fibrotic target in hepatic stellate cells
Wenyang Li, Robert P Sparks, Cheng Sun, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 17, 2012
Identification of novel series of pyrazole and indole-urea based DFG-out PYK2 inhibitors
Samit K Bhattacharya, Gary E Aspnes, Scott W Bagley, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 28, 2008
Trifluoromethylpyrimidine-based inhibitors of proline-rich tyrosine kinase 2 (PYK2): structure-activity relationships and strategies for the elimination of reactive metabolite formation
Daniel P Walker, F Christopher Bi, Amit S Kalgutkar, et al.
Journal of Medicinal Chemistry
|
September 9, 2015
Discovery and Optimization of Imidazopyridine-Based Inhibitors of Diacylglycerol Acyltransferase 2 (DGAT2)
Kentaro Futatsugi, Daniel W Kung, Suvi T M Orr, et al.
Journal of Medicinal Chemistry
|
February 22, 2018
Optimization of Metabolic and Renal Clearance in a Series of Indole Acid Direct Activators of 5'-Adenosine Monophosphate-Activated Protein Kinase (AMPK)
David J Edmonds, Daniel W Kung, Amit S Kalgutkar, et al.
Journal of Medicinal Chemistry
|
December 27, 2011
Discovery of (S)-6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid as a hepatoselective glucokinase activator clinical candidate for treating type 2 diabetes mellitus
Jeffrey A Pfefferkorn, Angel Guzman-Perez, John Litchfield, et al.
Page
of 9