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Bioorganic Chemistry|November 28, 2025
Design, synthesis, and anticancer evaluation of spirooxindole-1,2,3-triazole hybrids as potent VEGFR-2 inhibitorsAssem Barakat, Moayad Abdullah Alwehaibi, Abdulmajeed Abdullah Alayyaf, et al.
Frontiers in Chemistry|December 12, 2022
Pyrazolyl-s-triazine with indole motif as a novel of epidermal growth factor receptor/cyclin-dependent kinase 2 dual inhibitorsIhab Shawish, Mohamed S Nafie, Assem Barakat, et al.
Molecules (Basel, Switzerland)|February 12, 2021
Multifunctional Isosteric Pyridine Analogs-Based 2-Aminothiazole: Design, Synthesis, and Potential Phosphodiesterase-5 Inhibitory ActivityAbdel Haleem M Hussein, Ahmed A Khames, Abu-Bakr A El-Adasy, et al.
Frontiers in Chemistry|January 30, 2023
Corrigendum: Pyrazolyl-s-triazine with indole motif as a novel of epidermal growth factor receptor/cyclin-dependent kinase 2 dual inhibitorsIhab Shawish, Mohamed S Nafie, Assem Barakat, et al.
RSC Medicinal Chemistry|August 16, 2024
Exploiting spirooxindoles for dual DNA targeting/CDK2 inhibition and simultaneous mitigation of oxidative stress towards selective NSCLC therapy; synthesis, evaluation, and molecular modelling studiesMohammad Shahidul Islam, Refaah M Al-Jassas, Abdullah Mohammed Al-Majid, et al.
ACS Omega|July 25, 2022
Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)-<i>s</i>-triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling CascadesIhab Shawish, Assem Barakat, Ali Aldalbahi, et al.
Chemistry & Biodiversity|November 29, 2025
Indenoquinoxaline-Based Spiro-Heterocycles: Synthesis, Structural Characterization, MEDT Study, and Dual Inhibition of Kinase-Related Enzymes EGFR and VEGFR2Abdulmajeed Abdullah Alayyaf, Abdullah Saleh Alamary, Mohammad Shahidul Islam, et al.
Pharmaceutics|August 26, 2022
Acetic Acid Mediated for One-Pot Synthesis of Novel Pyrazolyl <i>s</i>-Triazine Derivatives for the Targeted Therapy of Triple-Negative Breast Tumor Cells (MDA-MB-231) <i>via</i> EGFR/PI3K/AKT/mTOR Signaling CascadesIhab Shawish, Assem Barakat, Ali Aldalbahi, et al.
Journal of Enzyme Inhibition and Medicinal Chemistry|March 12, 2020
Synthesis and characterisation of thiobarbituric acid enamine derivatives, and evaluation of their α-glucosidase inhibitory and anti-glycation activityM Ali, Assem Barakat, Ayman El-Faham, et al.
Frontiers in Chemistry|December 31, 2021
Design, Synthesis, Chemical and Biochemical Insights Into Novel Hybrid Spirooxindole-Based p53-MDM2 Inhibitors With Potential Bcl2 Signaling AttenuationYasmine M Abdel Aziz, Gehad Lotfy, Mohamed M Said, et al.
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