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Chemmedchem
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October 25, 2018
Selective Optimization of Pranlukast to Farnesoid X Receptor Modulators
Simone Schierle, Jurema Schmidt, Astrid Kaiser, et al.
The Lancet Regional Health. Europe
|
February 8, 2024
Efficacy of MP1032 in hospitalised patients with COVID-19- authors' reply
Petra Sager, Astrid Kaiser, Sara Schumann, et al.
Bioorganic & Medicinal Chemistry
|
July 21, 2018
Structural optimization and in vitro profiling of N-phenylbenzamide-based farnesoid X receptor antagonists
Jurema Schmidt, Simone Schierle, Leonie Gellrich, et al.
Archiv Der Pharmazie
|
June 5, 2026
Silymarin and Its Isolated Flavanonol Lignans Are Liver X Receptor Antagonists
Nils C Bandomir, Astrid Kaiser, Felix F Lillich, et al.
Chemmedchem
|
May 30, 2019
Computer-Assisted Selective Optimization of Side-Activities-from Cinalukast to a PPARα Modulator
Julius Pollinger, Simone Schierle, Sebastian Neumann, et al.
ACS Pharmacology & Translational Science
|
April 16, 2021
Differential Therapeutic Effects of FXR Activation, sEH Inhibition, and Dual FXR/sEH Modulation in NASH in Diet-Induced Obese Mice
Moritz Helmstädter, Jurema Schmidt, Astrid Kaiser, et al.
Journal of Medicinal Chemistry
|
October 23, 2025
Scaffold Fusion and SAR Transfer with a Chemical Language Model Generates Novel Liver X Receptor Modulators
Nils Christiaan Bandomir, Tim Hörmann, Annette Kärcher, et al.
Future Medicinal Chemistry
|
January 30, 2016
SAR studies on FXR modulators led to the discovery of the first combined FXR antagonistic/TGR5 agonistic compound
Christina Lamers, Daniel Merk, Matthias Gabler, et al.
Journal of Medicinal Chemistry
|
July 21, 2020
Design and Structural Optimization of Dual FXR/PPARδ Activators
Simone Schierle, Sebastian Neumann, Pascal Heitel, et al.
ACS Medicinal Chemistry Letters
|
February 19, 2021
A New FXR Ligand Chemotype with Agonist/Antagonist Switch
Moritz Helmstädter, Jan Vietor, Jana Sommer, et al.
Page
of 5
Search research articles
Search
Showing results (1-10 of 44) with videos related to
Sort By:
Page
of 5
Chemmedchem
|
October 25, 2018
Selective Optimization of Pranlukast to Farnesoid X Receptor Modulators
Simone Schierle, Jurema Schmidt, Astrid Kaiser, et al.
The Lancet Regional Health. Europe
|
February 8, 2024
Efficacy of MP1032 in hospitalised patients with COVID-19- authors' reply
Petra Sager, Astrid Kaiser, Sara Schumann, et al.
Bioorganic & Medicinal Chemistry
|
July 21, 2018
Structural optimization and in vitro profiling of N-phenylbenzamide-based farnesoid X receptor antagonists
Jurema Schmidt, Simone Schierle, Leonie Gellrich, et al.
Archiv Der Pharmazie
|
June 5, 2026
Silymarin and Its Isolated Flavanonol Lignans Are Liver X Receptor Antagonists
Nils C Bandomir, Astrid Kaiser, Felix F Lillich, et al.
Chemmedchem
|
May 30, 2019
Computer-Assisted Selective Optimization of Side-Activities-from Cinalukast to a PPARα Modulator
Julius Pollinger, Simone Schierle, Sebastian Neumann, et al.
ACS Pharmacology & Translational Science
|
April 16, 2021
Differential Therapeutic Effects of FXR Activation, sEH Inhibition, and Dual FXR/sEH Modulation in NASH in Diet-Induced Obese Mice
Moritz Helmstädter, Jurema Schmidt, Astrid Kaiser, et al.
Journal of Medicinal Chemistry
|
October 23, 2025
Scaffold Fusion and SAR Transfer with a Chemical Language Model Generates Novel Liver X Receptor Modulators
Nils Christiaan Bandomir, Tim Hörmann, Annette Kärcher, et al.
Future Medicinal Chemistry
|
January 30, 2016
SAR studies on FXR modulators led to the discovery of the first combined FXR antagonistic/TGR5 agonistic compound
Christina Lamers, Daniel Merk, Matthias Gabler, et al.
Journal of Medicinal Chemistry
|
July 21, 2020
Design and Structural Optimization of Dual FXR/PPARδ Activators
Simone Schierle, Sebastian Neumann, Pascal Heitel, et al.
ACS Medicinal Chemistry Letters
|
February 19, 2021
A New FXR Ligand Chemotype with Agonist/Antagonist Switch
Moritz Helmstädter, Jan Vietor, Jana Sommer, et al.
Page
of 5