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ACS Medicinal Chemistry Letters
|
February 21, 2019
Computer-Assisted Discovery and Structural Optimization of a Novel Retinoid X Receptor Agonist Chemotype
Pascal Heitel, Leonie Gellrich, Lena Kalinowsky, et al.
Journal of Medicinal Chemistry
|
April 17, 2018
Combined Approach of Backbone Amide Linking and On-Resin N-Methylation for the Synthesis of Bioactive and Metabolically Stable Peptides
Frank Wesche, Hélène Adihou, Astrid Kaiser, et al.
Journal of Medicinal Chemistry
|
June 24, 2021
Second-Generation Dual FXR/sEH Modulators with Optimized Pharmacokinetics
Moritz Helmstädter, Astrid Kaiser, Steffen Brunst, et al.
ACS Medicinal Chemistry Letters
|
September 19, 2019
A Novel Biphenyl-based Chemotype of Retinoid X Receptor Ligands Enables Subtype and Heterodimer Preferences
Julius Pollinger, Simone Schierle, Leonie Gellrich, et al.
The Lancet Regional Health. Europe
|
December 11, 2023
Efficacy and safety of MP1032 plus standard-of-care compared to standard-of-care in hospitalised patients with COVID-19: a multicentre, randomised double-blind, placebo-controlled phase 2a trial
Petra Sager, Astrid Kaiser, Sara Schumann, et al.
Scientific Reports
|
May 3, 2018
Allosteric modulation of the farnesoid X receptor by a small molecule
Matthias Gabler, Jan Kramer, Jurema Schmidt, et al.
Journal of Medicinal Chemistry
|
February 1, 2019
Tuning Nuclear Receptor Selectivity of Wy14,643 towards Selective Retinoid X Receptor Modulation
Julius Pollinger, Leonie Gellrich, Simone Schierle, et al.
Communications Chemistry
|
January 27, 2023
A triple farnesoid X receptor and peroxisome proliferator-activated receptor α/δ activator reverses hepatic fibrosis in diet-induced NASH in mice
Pascal Heitel, Giuseppe Faudone, Moritz Helmstädter, et al.
Bioorganic & Medicinal Chemistry
|
April 2, 2014
Anthranilic acid derivatives as novel ligands for farnesoid X receptor (FXR)
Daniel Merk, Matthias Gabler, Roberto Carrasco Gomez, et al.
ACS Medicinal Chemistry Letters
|
April 16, 2025
Fragment-Based Discovery of Drug-like LRH-1 Agonists
Alisa Lang, Niklas Ildefeld, Felix F Lillich, et al.
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Showing results (11-20 of 44) with videos related to
Sort By:
Page
of 5
ACS Medicinal Chemistry Letters
|
February 21, 2019
Computer-Assisted Discovery and Structural Optimization of a Novel Retinoid X Receptor Agonist Chemotype
Pascal Heitel, Leonie Gellrich, Lena Kalinowsky, et al.
Journal of Medicinal Chemistry
|
April 17, 2018
Combined Approach of Backbone Amide Linking and On-Resin N-Methylation for the Synthesis of Bioactive and Metabolically Stable Peptides
Frank Wesche, Hélène Adihou, Astrid Kaiser, et al.
Journal of Medicinal Chemistry
|
June 24, 2021
Second-Generation Dual FXR/sEH Modulators with Optimized Pharmacokinetics
Moritz Helmstädter, Astrid Kaiser, Steffen Brunst, et al.
ACS Medicinal Chemistry Letters
|
September 19, 2019
A Novel Biphenyl-based Chemotype of Retinoid X Receptor Ligands Enables Subtype and Heterodimer Preferences
Julius Pollinger, Simone Schierle, Leonie Gellrich, et al.
The Lancet Regional Health. Europe
|
December 11, 2023
Efficacy and safety of MP1032 plus standard-of-care compared to standard-of-care in hospitalised patients with COVID-19: a multicentre, randomised double-blind, placebo-controlled phase 2a trial
Petra Sager, Astrid Kaiser, Sara Schumann, et al.
Scientific Reports
|
May 3, 2018
Allosteric modulation of the farnesoid X receptor by a small molecule
Matthias Gabler, Jan Kramer, Jurema Schmidt, et al.
Journal of Medicinal Chemistry
|
February 1, 2019
Tuning Nuclear Receptor Selectivity of Wy14,643 towards Selective Retinoid X Receptor Modulation
Julius Pollinger, Leonie Gellrich, Simone Schierle, et al.
Communications Chemistry
|
January 27, 2023
A triple farnesoid X receptor and peroxisome proliferator-activated receptor α/δ activator reverses hepatic fibrosis in diet-induced NASH in mice
Pascal Heitel, Giuseppe Faudone, Moritz Helmstädter, et al.
Bioorganic & Medicinal Chemistry
|
April 2, 2014
Anthranilic acid derivatives as novel ligands for farnesoid X receptor (FXR)
Daniel Merk, Matthias Gabler, Roberto Carrasco Gomez, et al.
ACS Medicinal Chemistry Letters
|
April 16, 2025
Fragment-Based Discovery of Drug-like LRH-1 Agonists
Alisa Lang, Niklas Ildefeld, Felix F Lillich, et al.
Page
of 5