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Science Signaling
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April 4, 2023
Migration mediated by the oxysterol receptor GPR183 depends on arrestin coupling but not receptor internalization
Viktoria M S Kjær, Viktorija Daugvilaite, Tomasz M Stepniewski, et al.
Nature Communications
|
December 23, 2020
Structure of the dopamine D<sub>2</sub> receptor in complex with the antipsychotic drug spiperone
Dohyun Im, Asuka Inoue, Takaaki Fujiwara, et al.
Nature Communications
|
January 9, 2021
Thioesterase-mediated side chain transesterification generates potent Gq signaling inhibitor FR900359
Cornelia Hermes, René Richarz, Daniel A Wirtz, et al.
Nature
|
October 22, 2025
Designing allosteric modulators to change GPCR G protein subtype selectivity
Madelyn N Moore, Kelsey L Person, Valeria L Robleto, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
August 7, 2025
Discovery and development of an oral analgesic targeting the α2B adrenoceptor
Masayasu Toyomoto, Takashi Kurihara, Takayuki Nakagawa, et al.
Cell Reports
|
December 21, 2025
Mast cell-specific CysLT2 receptor signaling inhibits cysteinyl leukotriene-dependent mast cell activation and type 2 allergic lung inflammation
Jun Nagai, Madeline M Hastings, Airi Nishida, et al.
The Journal of Biological Chemistry
|
September 29, 2023
Gαs is dispensable for β-arrestin coupling but dictates GRK selectivity and is predominant for gene expression regulation by β2-adrenergic receptor
Valeria Burghi, Justine S Paradis, Adam Officer, et al.
Scientific Reports
|
May 31, 2020
Signal profiling of the β<sub>1</sub>AR reveals coupling to novel signalling pathways and distinct phenotypic responses mediated by β<sub>1</sub>AR and β<sub>2</sub>AR
Viktoriya Lukasheva, Dominic Devost, Christian Le Gouill, et al.
Nature Chemical Biology
|
June 26, 2025
Insights into G-protein coupling preference from cryo-EM structures of G<sub>q</sub>-bound PTH1R
Fumiya K Sano, Kota Shimizume, Kazuhiro Kobayashi, et al.
Nature Chemical Biology
|
November 21, 2022
Insights into distinct signaling profiles of the µOR activated by diverse agonists
Qianhui Qu, Weijiao Huang, Deniz Aydin, et al.
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of 36
Search research articles
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Showing results (311-320 of 353) with videos related to
Sort By:
Page
of 36
Science Signaling
|
April 4, 2023
Migration mediated by the oxysterol receptor GPR183 depends on arrestin coupling but not receptor internalization
Viktoria M S Kjær, Viktorija Daugvilaite, Tomasz M Stepniewski, et al.
Nature Communications
|
December 23, 2020
Structure of the dopamine D<sub>2</sub> receptor in complex with the antipsychotic drug spiperone
Dohyun Im, Asuka Inoue, Takaaki Fujiwara, et al.
Nature Communications
|
January 9, 2021
Thioesterase-mediated side chain transesterification generates potent Gq signaling inhibitor FR900359
Cornelia Hermes, René Richarz, Daniel A Wirtz, et al.
Nature
|
October 22, 2025
Designing allosteric modulators to change GPCR G protein subtype selectivity
Madelyn N Moore, Kelsey L Person, Valeria L Robleto, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
August 7, 2025
Discovery and development of an oral analgesic targeting the α2B adrenoceptor
Masayasu Toyomoto, Takashi Kurihara, Takayuki Nakagawa, et al.
Cell Reports
|
December 21, 2025
Mast cell-specific CysLT2 receptor signaling inhibits cysteinyl leukotriene-dependent mast cell activation and type 2 allergic lung inflammation
Jun Nagai, Madeline M Hastings, Airi Nishida, et al.
The Journal of Biological Chemistry
|
September 29, 2023
Gαs is dispensable for β-arrestin coupling but dictates GRK selectivity and is predominant for gene expression regulation by β2-adrenergic receptor
Valeria Burghi, Justine S Paradis, Adam Officer, et al.
Scientific Reports
|
May 31, 2020
Signal profiling of the β<sub>1</sub>AR reveals coupling to novel signalling pathways and distinct phenotypic responses mediated by β<sub>1</sub>AR and β<sub>2</sub>AR
Viktoriya Lukasheva, Dominic Devost, Christian Le Gouill, et al.
Nature Chemical Biology
|
June 26, 2025
Insights into G-protein coupling preference from cryo-EM structures of G<sub>q</sub>-bound PTH1R
Fumiya K Sano, Kota Shimizume, Kazuhiro Kobayashi, et al.
Nature Chemical Biology
|
November 21, 2022
Insights into distinct signaling profiles of the µOR activated by diverse agonists
Qianhui Qu, Weijiao Huang, Deniz Aydin, et al.
Page
of 36