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Nucleic Acids Research|July 16, 2020
PARP1 catalytic variants reveal branching and chain length-specific functions of poly(ADP-ribose) in cellular physiology and stress responseLisa Aberle, Annika Krüger, Julia M Reber, et al.
Nature Communications|July 29, 2021
Mechanistic insights into the three steps of poly(ADP-ribosylation) reversalJohannes Gregor Matthias Rack, Qiang Liu, Valentina Zorzini, et al.
Proceedings of the National Academy of Sciences of the United States of America|April 11, 2018
PARP-1 protects against colorectal tumor induction, but promotes inflammation-driven colorectal tumor progressionBastian Dörsam, Nina Seiwert, Sebastian Foersch, et al.
Nucleic Acids Research|December 8, 2017
The C-terminal domain of p53 orchestrates the interplay between non-covalent and covalent poly(ADP-ribosyl)ation of p53 by PARP1Arthur Fischbach, Annika Krüger, Stephanie Hampp, et al.
Proceedings of the National Academy of Sciences of the United States of America|June 12, 2013
Chemical and cytokine features of innate immunity characterize serum and tissue profiles in inflammatory bowel diseaseCharles G Knutson, Aswin Mangerich, Yu Zeng, et al.
Proceedings of the National Academy of Sciences of the United States of America|June 13, 2012
Infection-induced colitis in mice causes dynamic and tissue-specific changes in stress response and DNA damage leading to colon cancerAswin Mangerich, Charles G Knutson, Nicola M Parry, et al.
ALTEX|October 27, 2023
Acceptance criteria for new approach methods in toxicology and human health-relevant life science research - part IAnna-Katharina Holzer, Nadine Dreser, Giorgia Pallocca, et al.
Molecular Cell|May 21, 2021
Unrestrained poly-ADP-ribosylation provides insights into chromatin regulation and human diseaseEvgeniia Prokhorova, Thomas Agnew, Anne R Wondisford, et al.
Nucleic Acids Research|October 4, 2016
Analyzing structure-function relationships of artificial and cancer-associated PARP1 variants by reconstituting TALEN-generated HeLa PARP1 knock-out cellsLisa Rank, Sebastian Veith, Eva C Gwosch, et al.
Cell Metabolism|December 3, 2014
A high-fat diet and NAD(+) activate Sirt1 to rescue premature aging in cockayne syndromeMorten Scheibye-Knudsen, Sarah J Mitchell, Evandro F Fang, et al.
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