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Frontiers in Immunology|May 6, 2022
Can ERAP1 and ERAP2 Form Functional Heterodimers? A Structural Dynamics InvestigationAthanasios Papakyriakou, Anastasia Mpakali, Efstratios StratikosFrontiers in Immunology|November 4, 2024
Polymorphic positions 349 and 725 of the autoimmunity-protective allotype 10 of ER aminopeptidase 1 are key in determining its unique enzymatic propertiesGalateia Georgaki, Anastasia Mpakali, Myrto Trakada, et al.Cancers|January 7, 2021
The Role of Antigen Processing and Presentation in Cancer and the Efficacy of Immune Checkpoint Inhibitor ImmunotherapyAnastasia Mpakali, Efstratios StratikosFrontiers in Immunology|August 22, 2017
The Role of Conformational Dynamics in Antigen Trimming by Intracellular AminopeptidasesAthanasios Papakyriakou, Efstratios StratikosJournal of Immunology (Baltimore, Md. : 1950)|August 12, 2015
Crystal Structure of Insulin-Regulated Aminopeptidase with Bound Substrate Analogue Provides Insight on Antigenic Epitope Precursor Recognition and ProcessingAnastasia Mpakali, Emmanuel Saridakis, Karl Harlos, et al.Biochemistry|February 21, 2017
Critical Role of Interdomain Interactions in the Conformational Change and Catalytic Mechanism of Endoplasmic Reticulum Aminopeptidase 1Athanasios Stamogiannos, Zachary Maben, Athanasios Papakyriakou, et al.Current Pharmaceutical Design|November 21, 2009
A new role for Zn(II) aminopeptidases: antigenic peptide generation and destructionIrini Evnouchidou, Athanasios Papakyriakou, Efstratios StratikosJournal of Medicinal Chemistry|March 23, 2017
Ligand-Induced Conformational Change of Insulin-Regulated Aminopeptidase: Insights on Catalytic Mechanism and Active Site PlasticityAnastasia Mpakali, Emmanuel Saridakis, Karl Harlos, et al.Scientific Reports|August 14, 2021
The ERAP1 active site cannot productively access the N-terminus of antigenic peptide precursors stably bound onto MHC class IGeorge Mavridis, Anastasia Mpakali, Jerome Zoidakis, et al.ACS Medicinal Chemistry Letters|February 18, 2022
Inhibitor-Dependent Usage of the S1' Specificity Pocket of ER Aminopeptidase 2Anastasia Mpakali, Dimitris Georgiadis, Efstratios Stratikos, et al.Pageof 17