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Blood Advances|September 4, 2020
AMG 701 induces cytotoxicity of multiple myeloma cells and depletes plasma cells in cynomolgus monkeysRebecca L Goldstein, Ana Goyos, Chi-Ming Li, et al.Bioorganic & Medicinal Chemistry|September 16, 2008
Distinctive molecular inhibition mechanisms for selective inhibitors of human 11beta-hydroxysteroid dehydrogenase type 1Hua Tu, Jay P Powers, Jinsong Liu, et al.The Journal of Biological Chemistry|May 26, 2018
Molecular basis for the loss-of-function effects of the Alzheimer's disease-associated R47H variant of the immune receptor TREM2Athena Sudom, Santosh Talreja, Jean Danao, et al.Bioorganic & Medicinal Chemistry Letters|February 3, 2009
Synthesis and optimization of arylsulfonylpiperazines as a novel class of inhibitors of 11 beta-hydroxysteroid dehydrogenase type 1 (11 beta-HSD1)Daqing Sun, Zhulun Wang, Mario Cardozo, et al.Bioorganic & Medicinal Chemistry Letters|February 5, 2013
Inhibiting NF-κB-inducing kinase (NIK): discovery, structure-based design, synthesis, structure-activity relationship, and co-crystal structuresKexue Li, Lawrence R McGee, Ben Fisher, et al.The Journal of Biological Chemistry|November 28, 2012
An inhibitory antibody against dipeptidyl peptidase IV improves glucose tolerance in vivoJie Tang, Jiangwen Majeti, Athena Sudom, et al.Bioorganic & Medicinal Chemistry Letters|October 26, 2010
The synthesis and SAR of novel diarylsulfone 11β-HSD1 inhibitorsXuelei Yan, Zhulun Wang, Athena Sudom, et al.Bioorganic & Medicinal Chemistry Letters|February 3, 2009
Optimization of novel di-substituted cyclohexylbenzamide derivatives as potent 11 beta-HSD1 inhibitorsDustin L McMinn, Yosup Rew, Athena Sudom, et al.Journal of Medicinal Chemistry|November 21, 2023
Imidazolone as an Amide Bioisostere in the Development of β-1,3-<i>N</i>-Acetylglucosaminyltransferase 2 (B3GNT2) InhibitorsJeffrey J Jackson, Aaron C Siegmund, Wen-Ju Bai, et al.Journal of Medicinal Chemistry|June 17, 2008
Discovery of novel, potent benzamide inhibitors of 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1) exhibiting oral activity in an enzyme inhibition ex vivo modelLisa D Julian, Zhulun Wang, Tracy Bostick, et al.Pageof 3