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Cells|May 27, 2026
Limonoid 7-Deacetoxy-7-oxogedunin (CG-1) Attenuates RANKL-Induced Osteoclastogenesis via Inhibiting PI3K/Akt-NFATc1 AxisAtsushi Koike, Ko Fujimori
The FEBS Journal|January 16, 2021
Statins attenuate antiviral IFN-β and ISG expression via inhibition of IRF3 and JAK/STAT signaling in poly(I:C)-treated hyperlipidemic mice and macrophagesAtsushi Koike, Kaito Tsujinaka, Ko Fujimori
European Journal of Pharmacology|April 13, 2024
Involvement of necroptotic cell death in macrophages in progression of bleomycin and LPS-induced acute exacerbation of idiopathic pulmonary fibrosisAtsushi Koike, Kaoruko Hayashi, Ko Fujimori
Experimental Cell Research|May 1, 2019
Pan-caspase inhibitors induce necroptosis via ROS-mediated activation of mixed lineage kinase domain-like protein and p38 in classically activated macrophagesAtsushi Koike, Miho Hanatani, Ko Fujimori
Molecules (Basel, Switzerland)|May 1, 2019
A Limonoid, 7-Deacetoxy-7-Oxogedunin (CG-1) from Andiroba (<i>Carapa guianensis</i>, Meliaceae) Lowers the Accumulation of Intracellular Lipids in Adipocytes via Suppression of IRS-1/Akt-Mediated Glucose Uptake and a Decrease in GLUT4 ExpressionChihiro Matsumoto, Atsushi Koike, Reiko Tanaka, et al.
Biological & Pharmaceutical Bulletin|March 7, 2015
Nitric oxide is an important regulator of heme oxygenase-1 expression in the lipopolysaccharide and interferon-γ-treated murine macrophage-like cell line J774.1/JA-4Atsushi Koike, Isato Minamiguchi, Ko Fujimori, et al.
Biochemistry and Biophysics Reports|September 29, 2017
Influence of the culture medium on the production of nitric oxide and expression of inducible nitric oxide synthase by activated macrophages <i>in vitro</i>Tomoya Kawakami, Kana Kawamura, Ko Fujimori, et al.
Journal of Biochemistry|January 22, 2020
Bicarbonate enhances the inflammatory response by activating JAK/STAT signalling in LPS + IFN-γ-stimulated macrophagesTomoya Kawakami, Atsushi Koike, Toko Maehara, et al.
Neurotoxicology|June 2, 2021
Formononetin attenuates H<sub>2</sub>O<sub>2</sub>-induced cell death through decreasing ROS level by PI3K/Akt-Nrf2-activated antioxidant gene expression and suppressing MAPK-regulated apoptosis in neuronal SH-SY5Y cellsMayuko Sugimoto, Risa Ko, Hiromi Goshima, et al.
Biological & Pharmaceutical Bulletin|June 3, 2016
Simultaneous Addition of Shikonin and Its Derivatives with Lipopolysaccharide Induces Rapid Macrophage DeathAtsushi Koike, Makio Shibano, Hideya Mori, et al.
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